Rapid quality control of technetium-99m-2-methoxy isobutyl isonitrile (technetium-99m-sestamibi)

JI Hirsch, MW Watson - Journal of Nuclear Medicine Technology, 1996 - Soc Nuclear Med
Objective: Technetium-99m-sestamibi (99mTc-MIBI) is a radiopharmaceutical imaging agent
useful for assessing myocardial perfusion. We present a simple, rapid and accurate …

HPLC investigation of the radiochemical purity of 99m Tc-MIBI

B Taşdelen - Journal of Radioanalytical and Nuclear Chemistry, 2011 - akjournals.com
Abstract Technetium-99m-sestamibi (99m Tc-MIBI) is a small, lipophilic and cationic
compound used for myocardial perfusion imaging. In addition, 99m Tc-MIBI has been shown …

The effect of selected preparation variables on the radiochemical purity of 99mTc-sestamibi

JP Norenberg, MP Vaidya, WB Hladik… - Journal of nuclear …, 2005 - Soc Nuclear Med
Objective: Measurement of cardiac perfusion via agents such as 99mTc-sestamibi
(Cardiolite; DuPont-Merck Pharmaceutical Co., Inc.) is widely used in clinical nuclear …

A better method of quality control for technetium-99m sestamibi

R Hammes, S Kies, D Koblenski… - Journal of nuclear …, 1991 - Soc Nuclear Med
The accepted method of quality control for technetium-99m (99mTc) sestamibi as published
by the manufacturer requires the use of an aluminum oxide-coated plastic thin layer …

The effect on radiochemical purity of modifications to the method of preparation and dilution of 99mTc-sestamibi

M Cooper, K Dustan, L Rotureau - Nuclear medicine …, 2006 - journals.lww.com
Background 99m Tc-sestamibi is a useful radiopharmaceutical for myocardial perfusion
imaging, parathyroid imaging and breast tumour imaging. However, the preparation is time …

Evaluation of an alternative radiochemical purity testing method for technetium-99m-sestamibi

AL Luebke, DM Wilary, DW Mahoney… - Journal of Nuclear …, 2000 - Soc Nuclear Med
Objective: Our study evaluated the accuracy and reliability of 3 radiochemical purity (RCP)
measurement methods of 99mTc-sestamibi. A regular-sized (1.0 cm× 9.0 cm) Whatman 31 …

[PDF][PDF] Rapid preparation and quality control method for technetium-99m-2-methoxy isobutyl isonitrile (technetium-99m-sestamibi)

JC Hung, ME Wilson, ML Brown… - Journal of Nuclear …, 1991 - Soc Nuclear Med
Rapid Preparation and Quality Control Method for Technetium-9 9m—2-MethoxyIsobutyl
Isonitrile (Technetium.-99m-Sestamibi) Page 1 pharmaceutical during coronary occlusion (2—7).Tech …

A miniaturized rapid paper chromatographic procedure for quality control of technetium-99m sestamibi

M Patel, S Sadek, S Jahan, A Owunwanne - European journal of nuclear …, 1995 - Springer
A miniaturized rapid paper chromatographic technique (MRPC) for quality control of a
technetium-99m sestamibi preparation was developed and compared with the …

Comparison of four alternative radiochemical purity testing methods for 99Tcm-sestamibi

JC Hung, ME Wilson, MW Gebhard… - Nuclear medicine …, 1995 - journals.lww.com
Four different methods for determining the radiochemical purity (RCP) of 99 Tc m-sestamibi
have been proposed to replace the recommended thin-layer chromatography (TLC) method …

The presence of sodium nitrate in generator eluate decreases the radiochemical purity of 99mTc-sestamibi

T Métayé, T Rosenberg, J Guilhot… - Journal of nuclear …, 2012 - Soc Nuclear Med
A high radiochemical purity (RCP) is recommended for radiopharmaceutical compounds
used in the clinical practice of nuclear medicine. However, some preparations of 99mTc …