PET Radiopharmaceuticals: What's new, what's reimbursed, and what's next?

BN Clarke - Journal of nuclear medicine technology, 2018 - Soc Nuclear Med
The field of molecular imaging is undergoing a period of expansion. The number of
radiopharmaceutical ligands, therapeutic isotope combinations, and targets continues to …

Clinical applications of small-molecule PET radiotracers: current progress and future outlook

AL Vāvere, PJH Scott - Seminars in Nuclear Medicine, 2017 - Elsevier
Radiotracers, or radiopharmaceuticals, are bioactive molecules tagged with a radionuclide
used for diagnostic imaging or radiotherapy and, when a positron-emitting radionuclide is …

An introduction to newer PET diagnostic agents and related therapeutic radiopharmaceuticals

E Mantel, J Williams - Journal of Nuclear Medicine Technology, 2019 - Soc Nuclear Med
With new radiopharmaceuticals constantly in development, the field of nuclear medicine is
ever evolving. This continuing education article reviews some of the newer, less frequently …

[HTML][HTML] Insight into the Development of PET Radiopharmaceuticals for Oncology

J Lau, E Rousseau, D Kwon, KS Lin, F Bénard, X Chen - Cancers, 2020 - mdpi.com
While the development of positron emission tomography (PET) radiopharmaceuticals
closely follows that of traditional drug development, there are several key considerations in …

Pharmacological prerequisites for PET ligands and practical issues in preclinical PET research

SM Ametamey, M Honer - PET chemistry: the driving force in molecular …, 2007 - Springer
The development of PET radiopharmaceuticals for the non-invasive imaging of cancerous
lesions, brain receptors, transporters and enzymes started more than 25 years ago. But till …

PET chemistry: An introduction

TL Roß, SM Ametamey - Basic sciences of nuclear medicine, 2021 - Springer
In PET imaging, the major driving force is novel and innovative radiopharmaceuticals.
Access to such radiopharmaceuticals is given by the field of PET chemistry. PET chemistry …

The next generation of positron emission tomography radiopharmaceuticals in oncology

SL Rice, CA Roney, P Daumar, JS Lewis - Seminars in nuclear medicine, 2011 - Elsevier
Although 18 F-fluorodeoxyglucose (18 F-FDG) is still the most widely used positron emission
tomography (PET) radiotracer, there are a few well-known limitations to its use. The last …

PET radiochemistry and radiopharmacy

MS Jacobson, RA Steichen, PJ Peller - PET-CT and PET-MRI in Oncology …, 2012 - Springer
The vast majority of PET radiopharmaceuticals today are cyclotron produced. Carbon-11 (11
C), Nitrogen-13 (13 N), Oxygen-15 (15 O) products are created for in-house use only due to …

PET radiopharmaceuticals: state-of-the-art and future prospects

TJ Tewson, KA Krohn - Seminars in nuclear medicine, 1998 - Elsevier
In this review we provide a conceptual overview of radiopharmaceuticals containing positron-
emitting isotopes, not a catalog of radiopharmaceuticals or details of syntheses. We hope to …

Radiopharmaceuticals in preclinical and clinical development for monitoring of therapy with PET

MPS Dunphy, JS Lewis - Journal of Nuclear Medicine, 2009 - Soc Nuclear Med
This review article discusses PET agents, other than 18 F-FDG, with the potential to monitor
the response to therapy before, during, or after therapeutic intervention. This review deals …