Perfusion assessment in critical limb ischemia: principles for understanding and the development of evidence and evaluation of devices: a scientific statement from the …

S Misra, MH Shishehbor, EA Takahashi, HD Aronow… - Circulation, 2019 - Am Heart Assoc
There are> 12 million patients with peripheral artery disease in the United States. The most
severe form of peripheral artery disease is critical limb ischemia (CLI). The diagnosis and …

New radiotracers for imaging of vascular targets in angiogenesis-related diseases

H Hong, F Chen, Y Zhang, W Cai - Advanced drug delivery reviews, 2014 - Elsevier
Tremendous advances over the last several decades in positron emission tomography
(PET) and single photon emission computed tomography (SPECT) allow for targeted …

Re-assessing the enhanced permeability and retention effect in peripheral arterial disease using radiolabeled long circulating nanoparticles

CG England, HJ Im, L Feng, F Chen, SA Graves… - Biomaterials, 2016 - Elsevier
As peripheral arterial disease (PAD) results in muscle ischemia and neovascularization, it
has been claimed that nanoparticles can passively accumulate in ischemic tissues through …

Radiotracer imaging allows for noninvasive detection and quantification of abnormalities in angiosome foot perfusion in diabetic patients with critical limb ischemia …

JL Alvelo, X Papademetris… - Circulation …, 2018 - Am Heart Assoc
Background: Single photon emission computed tomography (SPECT)/computed
tomography (CT) imaging allows for assessment of skeletal muscle microvascular perfusion …

[HTML][HTML] Intraprocedural transcutaneous oxygen pressure and systolic toe pressure measurements during and after endovascular intervention in patients with chronic …

T Gunnarsson, H Lindgren, A Gottsäter… - European Journal of …, 2021 - Elsevier
Objective The aim of this study was to evaluate changes in transcutaneous oxygen pressure
(tcpO 2) and systolic toe pressure (TP) during endovascular intervention. Methods This was …

[HTML][HTML] SPECT and PET imaging of angiogenesis and arteriogenesis in pre-clinical models of myocardial ischemia and peripheral vascular disease

G Hendrikx, S Vöö, M Bauwens, MJ Post… - European Journal of …, 2016 - Springer
Purpose The extent of neovascularization determines the clinical outcome of coronary artery
disease and other occlusive cardiovascular disorders. Monitoring of neovascularization is …

Contemporary assessment of foot perfusion in patients with critical limb ischemia

E Benitez, BJ Sumpio, J Chin, BE Sumpio - Seminars in vascular surgery, 2014 - Elsevier
Significant progress in limb salvage for patients with peripheral arterial disease and critical
limb ischemia has occurred in the past 2 decades. Improved patient outcomes have resulted …

[HTML][HTML] Ethnic differences in the association between angiotensin-converting enzyme gene insertion/deletion polymorphism and peripheral vascular disease: a meta …

C Han, XK Han, FC Liu, JF Huang - Chronic diseases and translational …, 2017 - Elsevier
Background Several studies have investigated the association of angiotensin-converting
enzyme (ACE) gene insertion/deletion (I/D) polymorphism with peripheral vascular disease …

2D perfusion-angiography during endovascular intervention for critical limb threatening ischemia–A feasibility study

HN Pärsson, N Lundin… - JRSM Cardiovascular …, 2020 - journals.sagepub.com
Purpose Two-dimensional perfusion angiography is a new method to quantify and evaluate
tissue perfusion during endovascular intervention. The aim was to evaluate time-patterns …

[HTML][HTML] [15O] H2O PET: Potential or Essential for Molecular Imaging?

RHJA Slart, TS Martinez-Lucio, HH Boersma… - Seminars in Nuclear …, 2023 - Elsevier
Imaging water pathways in the human body provides an excellent way of measuring
accurately the blood flow directed to different organs. This makes it a powerful diagnostic …