High-efficiency production of radiopharmaceuticals via droplet radiochemistry: A review of recent progress

J Wang, RM van Dam - Molecular Imaging, 2020 - journals.sagepub.com
New platforms are enabling radiochemistry to be carried out in tiny, microliter-scale volumes,
and this capability has enormous benefits for the production of radiopharmaceuticals. These …

Digital microfluidics: a new paradigm for radiochemistry

PY Keng, RM van Dam - Molecular imaging, 2015 - journals.sagepub.com
The emerging technology of digital microfluidics is opening up the possibility of performing
radiochemistry at the microliter scale to produce tracers for positron emission tomography …

Performing multi-step chemical reactions in microliter-sized droplets by leveraging a simple passive transport mechanism

J Wang, PH Chao, S Hanet, RM van Dam - Lab on a Chip, 2017 - pubs.rsc.org
Despite the increasing importance of positron emission tomography (PET) imaging in
research and clinical management of disease, access to myriad new radioactive tracers is …

Human brown adipose tissue temperature and fat fraction are related to its metabolic activity

K Koskensalo, J Raiko, T Saari… - The Journal of …, 2017 - academic.oup.com
Abstract Background and Aim: The metabolic activity of human brown adipose tissue (BAT)
has been previously examined using positron emission tomography (PET). The aim of this …

Reliability of task-specific neuronal activation assessed with functional PET, ASL and BOLD imaging

L Rischka, GM Godbersen, V Pichler… - Journal of Cerebral …, 2021 - journals.sagepub.com
Mapping the neuronal response during cognitive processing is of crucial importance to gain
new insights into human brain function. BOLD imaging and ASL are established MRI …

[HTML][HTML] Flare on [18F]PSMA-1007 PET/CT after short-term androgen deprivation therapy and its correlation to FDG uptake: possible marker of tumor aggressiveness …

S Malaspina, O Ettala, T Tolvanen, J Rajander… - European Journal of …, 2023 - Springer
Purpose Short-term androgen deprivation therapy (ADT) is known to increase
heterogeneously prostate-specific membrane antigen (PSMA) expression. This …

[HTML][HTML] Comparison of: (2S,4R)-4-[18F]Fluoroglutamine, [11C]Methionine, and 2-Deoxy-2-[18F]Fluoro-D-Glucose and Two Small-Animal PET/CT Systems …

MWG Miner, H Liljenbäck, J Virta, S Helin… - Frontiers in …, 2021 - frontiersin.org
Purpose The three positron emission tomography (PET) imaging compounds:(2 S, 4 R)-4-
[18F] Fluoroglutamine ([18F] FGln), L-[methyl-11C] Methionine ([11C] Met), and 2-deoxy-2 …

Radiochemistry, PET imaging, and the internet of chemical things

S Thompson, MR Kilbourn, PJH Scott - ACS central science, 2016 - ACS Publications
The Internet of Chemical Things (IoCT), a growing network of computers, mobile devices,
online resources, software suites, laboratory equipment, synthesis apparatus, analytical …

[HTML][HTML] Evaluation of PET imaging as a tool for detecting neonatal hypoxic-ischemic encephalopathy in a preclinical animal model

E Saha, S Shimochi, T Keller, O Eskola… - Experimental …, 2024 - Elsevier
Hypoxic-ischemic encephalopathy due to insufficient oxygen delivery to brain tissue is a
leading cause of death or severe morbidity in neonates. The early recognition of the most …

[PDF][PDF] Compliance and initiative: A discussion on the relationship between standards and activities in radiopharmaceutical production

GAS Costa, JMA Silva, RG Soares, CM Modena… - Heliyon, 2024 - cell.com
This study investigated how a standard could become reality-based in a workplace where
certain types of deviations are not permitted, such as a radiopharmaceutical production unit …