The mechanisms underlying ribonucleoprotein (RNP) granule assembly, including the basis
for establishing and maintaining RNP granules with distinct composition, are unknown. One …

It was found that the absorbance and fluorescence of green fluorescent protein (GFP) mutants
are strongly pH dependent in aqueous solutions and intracellular compartments in living …

It is thought that the high protein density in the mitochondrial matrix results in severely
restricted solute diffusion and metabolite channeling from one enzyme to another without free …

Alzheimer's disease (AD) displays a long asymptomatic stage before dementia. We
characterize AD stage-associated molecular networks by profiling 14,513 proteins and 34,173 …

The precise annotation and accurate identification of neural structures are prerequisites for
studying mammalian brain function. The orientation of neurons and neural circuits is usually …

Members of the nuclear factor-κB (NF-κB) family of transcriptional regulators are central
mediators of the cellular inflammatory response. Although constitutive NF-κB signalling is …

Intermolecular interactions, including attractive and repulsive interactions, play a vital role in
manipulating functionalization of the materials from micro to macro dimensions. Despite …

X-ray-induced photodynamic therapy utilizes penetrating X-rays to activate reactive oxygen
species in deep tissues for cancer treatment, which combines the advantages of …

Deposition of insoluble protein aggregates is a hallmark of neurodegenerative diseases.
The universal presence of β-amyloid and tau in Alzheimer’s disease (AD) has facilitated …

EZH2 (the Enhancer of Zeste Homolog 2), as a key epigenetic regulator and EMT inducer,
participates in a variety of cancer metastasis. EZH2 stability is regulated by several types of …