The assessment of three methods to verify tracheal tube placement in the emergency setting

T Takeda, K Tanigawa, H Tanaka, Y Hayashi, E Goto… - Resuscitation, 2003 - Elsevier
We studied prospectively the reliability of clinical methods, end-tidal carbon dioxide (ETCO
2 ) detection, and the esophageal detector device (EDD) for verifying tracheal intubation in …

[PDF][PDF] FADS2-dependent fatty acid desaturation dictates cellular sensitivity to ferroptosis and permissiveness for hepatitis C virus replication

D Yamane, Y Hayashi, M Matsumoto, H Nakanishi… - Cell chemical …, 2022 - cell.com
The metabolic oxidative degradation of cellular lipids severely restricts replication of hepatitis
C virus (HCV), a leading cause of chronic liver disease, but little is known about the factors …

Tumor-specific delivery of BSH-3R for boron neutron capture therapy and positron emission tomography imaging in a mouse brain tumor model

Y Iguchi, H Michiue, M Kitamatsu, Y Hayashi… - Biomaterials, 2015 - Elsevier
Glioblastoma, a malignant brain tumor with poor disease outcomes, is managed in modern
medicine by multimodality therapy. Boron neutron capture therapy (BNCT) is an encouraging …

Viable piglets generated from porcine oocytes matured in vitro and fertilized by intracytoplasmic sperm head injection

…, N Kashiwazaski, A Takizawa, Y Hayashi… - Biology of …, 2003 - academic.oup.com
Intracytoplasmic sperm injection (ICSI) of a nonmotile cell into the ooplasm for assisted
fertilization is a highly specialized procedure for producing the next generation. The production of …

Acceptance of and attitudes towards human papillomavirus vaccination in Japanese mothers of adolescent girls

SJB Hanley, E Yoshioka, Y Ito, R Konno, Y Hayashi… - Vaccine, 2012 - Elsevier
To better understand how to achieve high uptake rates of human papillomavirus (HPV)
vaccination in Japan, we investigated acceptance of and attitudes towards HPV vaccination in …

[HTML][HTML] Semaphorin-5A maintains epithelial phenotype of malignant pancreatic cancer cells

S Saxena, A Purohit, ML Varney, Y Hayashi, RK Singh - BMC cancer, 2018 - Springer
Background Pancreatic cancer (PC) is a highly aggressive disease, and the lethality of this
disease stems from early metastatic dissemination where surgical removal cannot provide a …

Ablation of fatty acid desaturase 2 (FADS2) exacerbates hepatic triacylglycerol and cholesterol accumulation in polyunsaturated fatty acid‐depleted mice

Y Hayashi, HC Lee‐Okada, E Nakamura, N Tada… - FEBS …, 2021 - Wiley Online Library
Deficiency of polyunsaturated fatty acids (PUFAs) is known to induce hepatic steatosis.
However, it is not clearly understood which type of PUFA is responsible for the worsening of …

[HTML][HTML] Pathological and functional significance of Semaphorin-5A in pancreatic cancer progression and metastasis

S Saxena, Y Hayashi, L Wu, M Awaji, P Atri… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Semaphorin-5A (SEMA5A) has differential cell surface expression between normal and cancer
cells and represents an attractive target for therapeutic intervention in pancreatic cancer (…

FADS2 inhibition in essential fatty acid deficiency induces hepatic lipid accumulation via impairment of very low-density lipoprotein (VLDL) secretion

Y Hayashi, A Shimamura, T Ishikawa… - Biochemical and …, 2018 - Elsevier
Fatty acid desaturase 2 (FADS2) is responsible for the first desaturation reaction in the
synthesis of highly unsaturated fatty acids (HUFAs), such as arachidonic acid (20:4n-6) and …

[HTML][HTML] Quantification of collagen fiber properties in alcoholic liver fibrosis using polarization-resolved second harmonic generation microscopy

…, E Hase, H Takanari, Y Hayashi, Y Hayashi… - Scientific Reports, 2023 - nature.com
Liver fibrosis is assessed mainly by conventional staining or second harmonic generation (SHG)
microscopy, which can only provide collagen content in fibrotic area. We propose to use …