User profiles for Yukihiko Sonoda
 | Yukihiko SonodaYamagata University Verified email at med.id.yamagata-u.ac.jp Cited by 5219 |
Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma
The formation of human malignant gliomas is thought to involve the accumulation of multiple
genetic alterations. To define the function of specific alterations in glioma formation, we …
genetic alterations. To define the function of specific alterations in glioma formation, we …
Akt pathway activation converts anaplastic astrocytoma to glioblastoma multiforme in a human astrocyte model of glioma
Human malignant gliomas are thought to develop as the result of stepwise accumulations of
multiple genetic alterations. Recently, we showed that E6/E7-mediated inactivation of p53/…
multiple genetic alterations. Recently, we showed that E6/E7-mediated inactivation of p53/…
Analysis of IDH1 and IDH2 mutations in Japanese glioma patients
Y Sonoda, T Kumabe, T Nakamura, R Saito… - Cancer …, 2009 - Wiley Online Library
A recent study reported on mutations in the active site of the isocitrate dehydrogenase 1 (IDH1)
gene in several types of gliomas. All mutations detected resulted in an amino acid …
gene in several types of gliomas. All mutations detected resulted in an amino acid …
Effects of surgery with salvage stereotactic radiosurgery versus surgery with whole-brain radiation therapy in patients with one to four brain metastases (JCOG0504): a …
…, M Sumi, Y Miyakita, T Kumabe, Y Sonoda… - Journal of Clinical …, 2018 - ascopubs.org
Purpose Whereas whole-brain radiotherapy (WBRT) has been the standard treatment of
brain metastases (BMs), stereotactic radiosurgery (SRS) is increasingly preferred to avoid …
brain metastases (BMs), stereotactic radiosurgery (SRS) is increasingly preferred to avoid …
Impact of gross total resection in patients with WHO grade III glioma harboring the IDH 1/2 mutation without the 1p/19q co-deletion
T Kawaguchi, Y Sonoda, I Shibahara, R Saito… - Journal of neuro …, 2016 - Springer
The prognosis of patients with WHO grade III gliomas is highly dependent on their genomic
status such as the isocitrate dehydrogenase (IDH) 1/2 mutation and1p/19q co-deletion. …
status such as the isocitrate dehydrogenase (IDH) 1/2 mutation and1p/19q co-deletion. …
[HTML][HTML] Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of …
…, T Suzuki, H Nakamura, K Makino, Y Sonoda… - Acta neuropathologica …, 2018 - Springer
Extensive molecular analyses of ependymal tumors have revealed that supratentorial and
posterior fossa ependymomas have distinct molecular profiles and are likely to be different …
posterior fossa ependymomas have distinct molecular profiles and are likely to be different …
The Japan Society for Neuro-Oncology guideline on the diagnosis and treatment of central nervous system germ cell tumors
…, K Terashima, H Yokoo, K Fukuoka, Y Sonoda… - Neuro …, 2022 - academic.oup.com
Primary CNS germ cell tumors (GCTs) are rare neoplasms predominantly observed in the
pediatric and young adult populations. In line with the hypothesis that the primordial germ cell …
pediatric and young adult populations. In line with the hypothesis that the primordial germ cell …
Long-term survivors of glioblastoma: clinical features and molecular analysis
Y Sonoda, T Kumabe, M Watanabe, Y Nakazato… - Acta …, 2009 - Springer
Background Glioblastoma is a highly lethal neoplasm with a median survival of 12–14
months; only 2–5% of patients survive >3 years. Methods At our institute, patients with …
months; only 2–5% of patients survive >3 years. Methods At our institute, patients with …
Association between molecular alterations and tumor location and MRI characteristics in anaplastic gliomas
Y Sonoda, I Shibahara, T Kawaguchi, R Saito… - Brain tumor …, 2015 - Springer
The aim of this study was to determine if molecular alterations are associated with tumor
location and radiological characteristics in anaplastic gliomas. We performed a retrospective …
location and radiological characteristics in anaplastic gliomas. We performed a retrospective …
A randomized, double-blind, phase III trial of personalized peptide vaccination for recurrent glioblastoma
…, T Ueba, H Abe, T Tamiya, Y Sonoda… - Neuro …, 2019 - academic.oup.com
Background We conducted a phase III trial of personalized peptide vaccination (PPV) for
human leukocyte antigen (HLA)-A24+ recurrent glioblastoma to develop a new treatment …
human leukocyte antigen (HLA)-A24+ recurrent glioblastoma to develop a new treatment …