[HTML][HTML] The prevention and treatment of missing data in clinical trials

…, A Rotnitzky, D Scharfstein, WJ Shih… - … England Journal of …, 2012 - Mass Medical Soc
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[HTML][HTML] Problems in dealing with missing data and informative censoring in clinical trials

WJ Shih - Current controlled trials in cardiovascular medicine, 2002 - Springer
A common problem in clinical trials is the missing data that occurs when patients do not
complete the study and drop out without further measurements. Missing data cause the usual …

Association of SGLT2 inhibitors with cardiovascular and kidney outcomes in patients with type 2 diabetes: a meta-analysis

DK McGuire, WJ Shih, F Cosentino… - JAMA …, 2021 - jamanetwork.com
… Dr Shih reported serving as consultant to the scientific advisory committee of Merck. Drs
Gantz and Huyck reported being employees of Merck & Co, Inc, Kenilworth, New Jersey, and …

[HTML][HTML] Cardiovascular outcomes with ertugliflozin in type 2 diabetes

…, S Gallo, F Cosentino, WJ Shih… - … England Journal of …, 2020 - Mass Medical Soc
Background The cardiovascular effects of ertugliflozin, an inhibitor of sodium–glucose
cotransporter 2, have not been established. Methods In a multicenter, double-blind trial, we …

Comparison of new biochemical markers of bone turnover in late postmenopausal osteoporotic women in response to alendronate treatment

P Garnero, WJ Shih, E Gineyts, DB Karpf… - The Journal of …, 1994 - academic.oup.com
To evaluate the clinical utility of recently developed biochemical markers of bone turnover to
monitor the response of osteoporotic patients to antiresorptive therapy, we compared the …

Heart rate variability biofeedback increases baroreflex gain and peak expiratory flow

…, SE Lu, DL Eckberg, R Edelberg, WJ Shih… - Psychosomatic …, 2003 - journals.lww.com
Objective We evaluated heart rate variability biofeedback as a method for increasing vagal
baroreflex gain and improving pulmonary function among 54 healthy adults. Methods We …

Efficacy of ertugliflozin on heart failure–related events in patients with type 2 diabetes mellitus and established atherosclerotic cardiovascular disease: results of the …

…, R Frederich, B Charbonnel, J Mancuso, WJ Shih… - Circulation, 2020 - Am Heart Assoc
Background: In patients with type 2 diabetes mellitus, sodium-glucose cotransporter 2
inhibitors reduce the risk of hospitalization for heart failure (HHF). We assessed the effect of …

Group sequential designs using a family of type I error probability spending functions

IK Hwang, WJ Shih, JS De Cani - Statistics in medicine, 1990 - Wiley Online Library
Performing planned or unplanned interim analyses on accumulating data in clinical trials is
a frequent practice. In this paper, we propose a general one‐parameter family of type I error …

The CD44 receptor interacts with P-glycoprotein to promote cell migration and invasion in cancer

…, GN Saglimbeni, X Wu, J Yang, K Apolito, WJ Shih… - Cancer research, 2005 - AACR
Invasion and metastases of cancer cells and the development of resistance to anticancer
therapies are the main causes of morbidity and mortality from cancer. For more than two …

Inhibition of Intestinal Tumorigenesis in Apcmin/+ Mice by (−)-Epigallocatechin-3-Gallate, the Major Catechin in Green Tea

…, J Liao, G Yang, YY Liu, Z Hou, Y Lin, J Ma, WJ Shih… - Cancer research, 2005 - AACR
The present study was designed to investigate the effects of two main constituents of green
tea, (−)-epigallocatechin-3-gallate (EGCG) and caffeine, on intestinal tumorigenesis in Apc …