User profiles for Travis W. Sawyer

Travis William Sawyer

University of Arizona
Verified email at email.arizona.edu
Cited by 320

[HTML][HTML] Ovarian cancer detection using optical coherence tomography and convolutional neural networks

D Schwartz, TW Sawyer, N Thurston, J Barton… - Neural Computing and …, 2022 - Springer
Ovarian cancer has the sixth-largest fatality rate in the United States among all cancers. A
non-surgical assay capable of detecting ovarian cancer with acceptable sensitivity and …

Three-dimensional texture analysis of optical coherence tomography images of ovarian tissue

TW Sawyer, S Chandra, PFS Rice… - Physics in Medicine …, 2018 - iopscience.iop.org
Ovarian cancer has the lowest survival rate among all gynecologic cancers due to predominantly
late diagnosis. Optical coherence tomography (OCT) has been applied successfully to …

Opti-MSFA: a toolbox for generalized design and optimization of multispectral filter arrays

TW Sawyer, M Taylor-Williams, R Tao, R Xia… - Optics …, 2022 - opg.optica.org
Multispectral imaging captures spatial information across a set of discrete spectral channels
and is widely utilized across diverse applications such as remote sensing, industrial …

[HTML][HTML] GFAP-directed inactivation of Men1 exploits glial cell plasticity in favor of neuroendocrine reprogramming

S Duan, TW Sawyer, RA Sontz, BA Wieland… - Cellular and molecular …, 2022 - Elsevier
Background & Aims Efforts to characterize the signaling mechanisms that underlie
gastroenteropancreatic neoplasms (GEP-NENs) are precluded by a lack of comprehensive models …

Evaluation of illumination system uniformity for wide-field biomedical hyperspectral imaging

TW Sawyer, AS Luthman, SE Bohndiek - Journal of Optics, 2017 - iopscience.iop.org
Hyperspectral imaging (HSI) systems collect both spatial (morphological) and spectral (chemical)
information from a sample. HSI can provide sensitive analysis for biological and …

Evaluating backscattering polarized light imaging microstructural mapping capabilities through neural tissue and analogous phantom imaging

…, AL Twer, E Hutchinson, TW Sawyer - Journal of …, 2024 - spiedigitallibrary.org
Significance Knowledge of fiber microstructure and orientation in the brain is critical for
many applications. Polarized light imaging (PLI) has been shown to have potential for better …

[HTML][HTML] Backscattering Mueller Matrix polarimetry on whole brain specimens shows promise for minimally invasive mapping of microstructural orientation features

…, C Comrie, N Daigle, E Hutchinson, TW Sawyer - Frontiers in …, 2022 - frontiersin.org
Understanding microscale physiology and microstructural cellular features of the brain is
key to understanding mechanisms of neurodegenerative diseases and injury, as well as …

Spatial profiling reveals tissue‐specific neuro‐immune interactions in gastroenteropancreatic neuroendocrine tumors

S Duan, TW Sawyer, BL Witten, H Song… - The Journal of …, 2024 - Wiley Online Library
Gastroenteropancreatic neuroendocrine tumors (GEP‐NETs) are heterogeneous malignancies
that arise from complex cellular interactions within the tissue microenvironment. Here, we …

Quantification of multiphoton and fluorescence images of reproductive tissues from a mouse ovarian cancer model shows promise for early disease detection

TW Sawyer, JW Koevary, FPS Rice… - … of biomedical optics, 2019 - spiedigitallibrary.org
Ovarian cancer is the deadliest gynecologic cancer due predominantly to late diagnosis. Early
detection of ovarian cancer can increase 5-year survival rates from 40% up to 92%, yet no …

Fluorescence and multiphoton imaging for tissue characterization of a model of postmenopausal ovarian cancer

TW Sawyer, JW Koevary, CC Howard… - Lasers in surgery …, 2020 - Wiley Online Library
Background and Objectives To determine the efficacy of targeted fluorescent biomarkers
and multiphoton imaging to characterize early changes in ovarian tissue with the onset of …