Objective The use of cannabis as a therapeutic agent for various medical conditions has
been well documented. However, clinical trials in patients with Parkinson disease (PD) have …

Parkinsonism in patients taking neuroleptic medications might be induced by dopamine
receptor blockade alone or by dopamine blockade with nigrostriatal dysfunction. The …

Background and Purpose We undertook to estimate the frequency of various risk factors
and the type and severity of stroke in different ethnic groups documented in a large hospital-…

Background and Purpose—There is a growing interest in the use of genetic markers in the
differential diagnosis of dementia. In the current study we examined the usefulness of genetic …

Despite its low efficacy, aspirin is the most widely used drug for secondary stroke prevention.
The reasons why stroke recurs while patients are on aspirin are unknown. We have …

The increasing prevalence with age of antiphospholipid antibodies (aPL), of dementia and
of stroke complicates the study of a causal relationship between antiphospholipid syndrome (…

Molecular imaging studies of Parkinson's disease (PD) progression mostly focus on the first
5 years after disease onset, demonstrating rapid initial nigrostriatal neuronal loss. The fate of …

Sample size calculations are important for planning drug trials and require anticipation of
the proportion of potential patients finally recruited. Because most recent drug studies for …

Objective.—To evaluate the efficacy and safety of dihydroergotamine (DHE) nasal spray in
patients suffering from common or classical migraine. Methods.—In a double‐blind parallel‐…

Germline mutations in the presenilin 1 (PS1) gene apparently account for the majority of
early-onset, familial Alzheimer’s disease (AD). Using a mutation-screening strategy (denaturing …