The NINCDS–ADRDA and the DSM-IV-TR criteria for Alzheimer's disease (AD) are the
prevailing diagnostic standards in research; however, they have now fallen behind the …

Objective: The goal of this project was to determine whether screening different groups of
elderly individuals in a general or specialty practice would be beneficial in detecting dementia. …

Cerebrovascular disease is the second most common cause of acquired cognitive impairment
and dementia and contributes to cognitive decline in the neurodegenerative dementias. …

The National Institute on Aging and the Alzheimer’s Association charged a workgroup with
the task of developing criteria for the symptomatic predementia phase of Alzheimer’s disease (…

The Alzheimer Disease Genetics Consortium (ADGC) performed a genome-wide association
study of late-onset Alzheimer disease using a three-stage design consisting of a discovery …

In the past 8 years, both the International Working Group (IWG) and the US National Institute
on Aging–Alzheimer's Association have contributed criteria for the diagnosis of Alzheimer's …

Ultrastructural studies of biopsied cortical tissue from the right frontal lobe of 8 patients with
mild to moderate Alzheimer's disease (AD) revealed that the number of synapses in lamina III …

Alzheimer's disease (AD) is classically defined as a dual clinicopathological entity. The recent
advances in use of reliable biomarkers of AD that provide in-vivo evidence of the disease …

Objective: To update the 1994 practice parameter for the diagnosis of dementia in the elderly.
Background: The AAN previously published a practice parameter on dementia in 1994. …

Objectives Amyloid‐β 42 (Aβ 42 ) appears central to Alzheimer's disease (AD) pathogenesis
and is a major component of amyloid plaques. Mean cerebrospinal fluid (CSF) Aβ 42 is …