Objective We have previously reported an automated method for within-modality (eg, PET-to-PET)
image alignment. We now describe modifications to this method that allow for cross-…

MicroPET is a high resolution positron emission tomography (PET) scanner designed for
imaging small laboratory animals. It consists of a ring of 30 position-sensitive scintillation …

A computer algorithm for the three-dimensional (3D) alignment of PET images is described.
To align two images, the algorithm calculates the ratio of one image to the other on a voxel-…

Noninvasive imaging at the molecular level is an emerging field in biomedical research.
This paper introduces a new technology synergizing two leading imaging methodologies: …

The emerging and rapidly growing field of molecular and genomic imaging is providing new
opportunities to directly visualize the biology of living organisms. By combining our growing …

Purpose We sought to describe and validate an automated image registration method (AIR
3.0) based on matching of voxel intensities. Method Different cost functions, different …

Cherry, Sorenson, and Phelps’ Physics in Nuclear Medicine is perhaps the best-known
textbook on the subject and continues to be the text of choice for many education programs in …

introduced. The methods by which PET data are reconstructed into a three-dimensional
image volume are explained, along with some of the approaches that are used to analyze and …

A Bayesian method is described for reconstruction of high-resolution 3D images from the
microPET small-animal scanner. Resolution recovery is achieved by explicitly modelling the …

PET is widely considered the most sensitive technique available for noninvasively studying
physiology, metabolism, and molecular pathways in the living human being. However, the …