Quality improvement initiatives to assess and improve PET/CT injection infiltration rates at multiple centers

…, KA Ryan, SR Perrin, RK Lattanze… - Journal of nuclear …, 2019 - Soc Nuclear Med
PET/CT radiotracer infiltration is not uncommon and is often outside the imaging field of view.
Infiltration can negatively affect image quality, image quantification, and patient …

Novel method to detect and characterize 18F-FDG infiltration at the injection site: a single-institution experience

…, SA Frye, A McMunn, K Ryan, R Lattanze… - Journal of nuclear …, 2017 - Soc Nuclear Med
A novel quality control and quality assurance device provides time–activity curves that can
identify and characterize PET/CT radiotracer infiltration at the injection site during the uptake …

[HTML][HTML] Impact of an 18F-FDG PET/CT radiotracer injection infiltration on patient management—a case report

JW Kiser, JR Crowley, DA Wyatt, RK Lattanze - Frontiers in Medicine, 2018 - frontiersin.org
Major management decisions in patients with solid tumors and lymphomas are often based
on 18F-fluorodeoxyglucose (18F-FDG) PET/CT. The misadministration of 18F-FDG outside …

Towards real-time topical detection and characterization of FDG dose infiltration prior to PET imaging

…, WJ Gorge, JG Knowland, RK Lattanze… - European journal of …, 2016 - Springer
Purpose To dynamically detect and characterize 18 F-fluorodeoxyglucose (FDG) dose
infiltrations and evaluate their effects on positron emission tomography (PET) standardized …

[HTML][HTML] Usefulness of topically applied sensors to assess the quality of 18F-FDG injections and validation against dynamic positron emission tomography (PET) …

RK Lattanze, MM Osman, KA Ryan, S Frye… - Frontiers in …, 2018 - frontiersin.org
Background: Infiltrations of 18F-fluorodeoxyglucose (FDG) injections affect positron emission
tomography/computed tomography (PET/CT) image quality and quantification. A device …

[HTML][HTML] The scientific and clinical case for reviewing diagnostic radiopharmaceutical extravasation long-standing assumptions

D Osborne, R Lattanze, J Knowland, TE Bryant… - Frontiers in …, 2021 - frontiersin.org
Background: The patient benefit from a diagnostic nuclear medicine procedure far outweighs
the associated radiation risk. This benefit/risk ratio assumes a properly administered …

Practical clinical measurement of radiotracer concentration in blood: initial device concept and feasibility testing

J Knowland, R Lattanze, J Kingg… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Kinetic analysis of PET data requires continuous measurement of radioactivity in the arterial
blood throughout the acquisition time, termed the arterial input function. The arterial input …

Multi-center assessment of infiltration rates in FDG-PET/CT scans: detection, incidence, and contributing factors

D Townsend, T Benefield, S Perrin, K Ryan, R Lattanze… - 2018 - Soc Nuclear Med
520 Objectives: 18 F-FDG dose infiltration impacts PET/CT image quality and quantification
accuracy. However, standardized Quality Control (QC) or Quality Assurance (QA) have not …

Characterization of technology to detect residual injection site radioactivity

J Knowland, S Lipman, R Lattanze, J Kingg… - Medical …, 2019 - Wiley Online Library
Purpose Each year in the United States, approximately 18.5 million nuclear medicine
procedures are performed. Various quality control measures are implemented to reduce image …

Assessing and reducing positron emission tomography/computed tomography radiotracer infiltrations: lessons in quality improvement and sustainability

JW Kiser, T Benefield, RK Lattanze, KA Ryan… - JCO oncology …, 2020 - ascopubs.org
PURPOSE: Accurate administration of radiotracer dose is essential to positron emission
tomography (PET) image quality and quantification. Misadministration (infiltration) of the dose …