User profiles for Robert R Flavell

Robert R. Flavell

Assistant Professor, University of California, San Francisco
Verified email at ucsf.edu
Cited by 3252

[HTML][HTML] Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome

…, N Chevalier, C Ang, E Marino, R Robert… - Nature …, 2015 - nature.com
Diet and the gut microbiota may underpin numerous human diseases. A major metabolic
product of commensal bacteria are short-chain fatty acids (SCFAs) that derive from …

Assessment of 68Ga-PSMA-11 PET accuracy in localizing recurrent prostate cancer: a prospective single-arm clinical trial

WP Fendler, J Calais, M Eiber, RR Flavell… - JAMA …, 2019 - jamanetwork.com
Importance In retrospective studies, 68 Ga-PSMA-11 positron emission tomographic (PET)
imaging improves detection of biochemically recurrent prostate cancer compared with …

A Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using 18F-FDG PET of the Brain

…, MS Aboian, C Mari Aparici, SC Behr, RR Flavell… - Radiology, 2019 - pubs.rsna.org
Purpose To develop and validate a deep learning algorithm that predicts the final diagnosis
of Alzheimer disease (AD), mild cognitive impairment, or neither at fluorine 18 ( 18 F) …

Impact of 68Ga-PSMA-11 PET on the management of recurrent prostate cancer in a prospective single-arm clinical trial

…, J Czernin, M Eiber, RR Flavell… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) ligand PET induces management changes in
patients with prostate cancer. We aim to better characterize the impact of 68 Ga-PSMA-11 …

Expressed protein ligation (EPL) in the study of signal transduction, ion conduction, and chromatin biology

RR Flavell, TW Muir - Accounts of chemical research, 2009 - ACS Publications
Expressed protein ligation (EPL) is a semisynthetic technique in which a recombinant protein
thioester, generated by thiolysis of an intein fusion protein, is reacted with a synthetic or …

Chemoenzymatic Syntheses of Fluorine-18-Labeled Disaccharides from [18F] FDG Yield Potent Sensors of Living Bacteria In Vivo

…, RR Flavell, OS Rosenberg, R Sriram… - Journal of the …, 2023 - ACS Publications
Chemoenzymatic techniques have been applied extensively to pharmaceutical
development, most effectively when routine synthetic methods fail. The regioselective and …

Nuclear imaging of bacterial infection: the state of the art and future directions

I Polvoy, RR Flavell, OS Rosenberg… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Increased mortality rates from infectious diseases is a growing public health concern. Successful
management of acute bacterial infections requires early diagnosis and treatment, which …

[HTML][HTML] First-in-human immunoPET imaging of HIV-1 infection using 89Zr-labeled VRC01 broadly neutralizing antibody

DR Beckford-Vera, RR Flavell, Y Seo… - Nature …, 2022 - nature.com
A major obstacle to achieving long-term antiretroviral (ART) free remission or functional cure
of HIV infection is the presence of persistently infected cells that establish a long-lived viral …

[HTML][HTML] Imaging Active Infection in vivo Using D-Amino Acid Derived PET Radiotracers

…, CA Mutch, RR Flavell, JE Blecha, T Kwak, R Sriram… - Scientific reports, 2017 - nature.com
Occult bacterial infections represent a worldwide health problem. Differentiating active
bacterial infection from sterile inflammation can be difficult using current imaging tools. Present …

Treatment of Prostate Cancer with CD46-targeted 225Ac Alpha Particle Radioimmunotherapy

…, HF VanBrocklin, Y Seo, J Chou, B Liu, RR Flavell - Clinical Cancer …, 2023 - AACR
Purpose: Radiopharmaceutical therapy is changing the standard of care in prostate cancer
and other malignancies. We previously reported high CD46 expression in prostate cancer …