User profiles for Peter J. H. Scott
Peter JH ScottUniversity of Michigan Verified email at umich.edu Cited by 6401 |
Copper-mediated late-stage radiofluorination: five years of impact on preclinical and clinical PET imaging
Purpose Copper-mediated radiofluorination (CMRF) is emerging as the method of choice
for the formation of aromatic C– 18 F bonds. This minireview examines proof-of-concept, …
for the formation of aromatic C– 18 F bonds. This minireview examines proof-of-concept, …
Radiosyntheses using fluorine-18: the art and science of late stage fluorination
…, R Littich, R Hoareau, P JH Scott - Current topics in …, 2014 - ingentaconnect.com
Positron (β+) emission tomography (PET) is a powerful, noninvasive tool for the in vivo, three-dimensional
imaging of physiological structures and biochemical pathways. The continued …
imaging of physiological structures and biochemical pathways. The continued …
Iridium‐Catalysed C− H Borylation of Heteroarenes: Balancing Steric and Electronic Regiocontrol
The iridium‐catalysed borylation of aromatic C−H bonds has become the preferred method
for the synthesis of aromatic organoboron compounds. The reaction is highly efficient, …
for the synthesis of aromatic organoboron compounds. The reaction is highly efficient, …
Copper-Mediated Radiofluorination of Arylstannanes with [18F]KF
A copper-mediated nucleophilic radiofluorination of aryl- and vinylstannanes with [ 18 F]KF
is described. This method is fast, uses commercially available reagents, and is compatible …
is described. This method is fast, uses commercially available reagents, and is compatible …
Late-stage [18 F] fluorination: new solutions to old problems
…, JJ Topczewski, N Ichiishi, MS Sanford, PJH Scott - Chemical …, 2014 - pubs.rsc.org
The last 2–3 years have seen numerous relationships develop between organometallic
chemists, fluorine chemists and PET Centers around the world. These collaborations have led to …
chemists, fluorine chemists and PET Centers around the world. These collaborations have led to …
Synthesis of [18F]Arenes via the Copper-Mediated [18F]Fluorination of Boronic Acids
…, JM Miller, N Ichiishi, MS Sanford, PJH Scott - Organic …, 2015 - ACS Publications
A copper-mediated radiofluorination of aryl- and vinylboronic acids with K 18 F is described.
This method exhibits high functional group tolerance and is effective for the radiofluorination …
This method exhibits high functional group tolerance and is effective for the radiofluorination …
Cu-Mediated C–H 18F-Fluorination of Electron-Rich (Hetero)arenes
This communication describes a method for the nucleophilic radiofluorination of electron-rich
arenes. The reaction involves the initial C(sp 2 )–H functionalization of an electron-rich …
arenes. The reaction involves the initial C(sp 2 )–H functionalization of an electron-rich …
Copper-Catalyzed [18F]Fluorination of (Mesityl)(aryl)iodonium Salts
…, ME Rodnick, MS Sanford, PJH Scott - Organic …, 2014 - ACS Publications
A practical, rapid, and highly regioselective Cu-catalyzed radiofluorination of (mesityl)(aryl)iodonium
salts is described. This protocol utilizes [ 18 F]KF to access 18 F-labeled electron-…
salts is described. This protocol utilizes [ 18 F]KF to access 18 F-labeled electron-…
Gait speed in Parkinson disease correlates with cholinergic degeneration
Objective: We investigated dopaminergic and cholinergic correlates of gait speed in Parkinson
disease (PD) and non-PD control subjects to test the hypothesis that gait dysfunction in …
disease (PD) and non-PD control subjects to test the hypothesis that gait dysfunction in …
Synthesis of 68Ga-radiopharmaceuticals using both generator-derived and cyclotron-produced 68Ga as exemplified by [68Ga]Ga-PSMA-11 for prostate cancer PET …
[ 68 Ga]Ga-PSMA-11, a urea-based peptidomimetic, is a diagnostic radiopharmaceutical for
positron emission tomography (PET) imaging that targets the prostate-specific membrane …
positron emission tomography (PET) imaging that targets the prostate-specific membrane …