Background The antimicrobial concentration required to kill all the bacteria in a biofilm, known
as the minimum biofilm eradication concentration (MBEC), is typically determined in vitro …

The medial prefrontal cortex (mPFC) and nucleus accumbens (NAc) are 2 structures within
a larger corticolimbic network mediating goal-directed actions, especially when the …

Background Early intramuscular administration of SARS-CoV-2-neutralising monoclonal
antibody combination, tixagevimab–cilgavimab, to non-hospitalised adults with mild to …

Recent case-series of small size implied a pathophysiological association between coronavirus
disease 2019 (COVID-19) and severe large-vessel acute ischemic stroke. Given that …

Purpose Currently, there is no consensus on the optimal treatment for scaphoid nonunion
with avascular necrosis (AVN). Various techniques, often involving vascularized …

Background: Bacterial biofilms cause chronic orthopaedic infections. Surgical debridement
to remove biofilm can be ineffective without adjuvant local antimicrobials because …

Background Headless screw fixation is the current gold standard of surgical repair for
scaphoid fractures. However, maintaining reduction of certain types of scaphoid fractures is …

Introduction Carbapenemases are β-lactamases able to hydrolyze a wide range of β-lactam
antibiotics, including carbapenems. Carbapenemase production in Enterobacterales, …

Background: Greater trochanter decortication is frequently performed at the time of abductor
tendon repair to theoretically increase healing potential. No previous studies have …

Background Studies have shown that more than 50% of the antibiotics used in hospitals are
unnecessary or inappropriate and, that antimicrobial resistance may cost up to 20 billion …