User profiles for Parul Thakral

parul thakral

Fortis Memorial Research Institute
Verified email at fortishealthcare.com
Cited by 282

Dosimetric analyses of kidneys, liver, spleen, pituitary gland, and neuroendocrine tumors of patients treated with 177Lu-DOTATATE

SK Gupta, S Singla, P Thakral, C Bal - Clinical nuclear medicine, 2013 - journals.lww.com
Objectives The aim of this work was to calculate the radiation absorbed dose to kidneys, liver,
spleen, pituitary gland, and neuroendocrine tumors (NETs) of patients treated with 177 Lu-…

[HTML][HTML] In-house preparation and quality control of Ac-225 prostate-specific membrane antigen-617 for the targeted alpha therapy of castration-resistant prostate …

P Thakral, J Simecek, S Marx, J Kumari… - Indian Journal of …, 2021 - journals.lww.com
Purpose: Ac-225 labeled with prostate-specific membrane antigen (PSMA-617), a transmembrane
glycoprotein which is highly expressed in prostate carcinoma cells, is presently being …

Actinium-225-PSMA radioligand therapy of metastatic castration-resistant prostate cancer (WARMTH Act): a multicentre, retrospective study

…, IB Sen, A Singh, A Sood, R Tauber, P Thakral… - The Lancet …, 2024 - thelancet.com
Background Actinium-225 ( 225 Ac) prostate-specific membrane antigen (PSMA) radioligand
therapy (RLT) is a novel therapy for metastatic castration-resistant prostate cancer (mCRPC…

Dosimetric analysis of patients with gastro entero pancreatic neuroendocrine tumors (NETs) treated with PRCRT (peptide receptor chemo radionuclide therapy) using …

P Thakral, I Sen, V Pant, SK Gupta… - The British journal of …, 2018 - academic.oup.com
Objective: Two radiosensitizing chemotherapeutic drugs, capecitabine (CAP) and temozolomide
(TEM), are administered concurrently to enhance the therapeutic efficacy of peptide …

Dosimetric analyses of intra-arterial versus standard intravenous administration of 177Lu-DOTATATE in patients of well differentiated neuroendocrine tumor with liver …

P Thakral, I Sen, SS Das, D Manda… - The British Journal of …, 2021 - academic.oup.com
Objective: The aim of the present study was to perform calculation of the absorbed doses to
organs at risk and to neuroendocrine tumors and to determine whether hepatic intra-arterial (…

Therapeutic efficacy of 225Ac-PSMA-617 targeted alpha therapy in patients of metastatic castrate resistant prostate cancer after taxane-based chemotherapy

I Sen, P Thakral, P Tiwari, V Pant, SS Das… - Annals of Nuclear …, 2021 - Springer
Objectives 225 Ac-PSMA-617 therapy has shown good response in many recent studies. We
report our experience of targeted alpha therapy with 225 Ac-PSMA-617 in mCRPC patients …

[HTML][HTML] An approach for conjugation of 177Lu-DOTA-SCN-Rituximab (BioSim) & its evaluation for radioimmunotherapy of relapsed & refractory B-cell non Hodgkins …

P Thakral, S Singla, MP Yadav, A Vasisht… - Indian Journal of …, 2014 - journals.lww.com
Methods: Rituximab (BioSim) was desalted with sodium bicarbonate (0.1 M, pH 9.0) and
incubated with DOTA-SCN (1: 50). The effectiveness of the conjugation was evaluated by …

Quality Assurance Considerations in Radiopharmaceutical Therapy Dosimetry Using PLANETDose: An International Atomic Energy Agency Study

…, TCG Moalosi, GL Poli, P Thakral… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Implementation of radiopharmaceutical therapy dosimetry varies depending on the clinical
application, dosimetry protocol, software, and ultimately the operator. Assessing clinical …

[HTML][HTML] The Role of PET-CT-Guided Metabolic Biopsies in Improving Yield of Inconclusive Anatomical Biopsies: A Review of 5 Years in a Teaching Hospital

D Malik, V Pant, I Sen, P Thakral, SS Das, V Cb - Diagnostics, 2023 - mdpi.com
Tumour sampling is indispensable to diagnostic and therapeutic decision making. Thus, 18F-FDG
PET/CT has the potential to accurately discriminate between viable and non-viable …

[HTML][HTML] Rare sites of metastases in prostate cancer detected on Ga-68 PSMA PET/CT scan—a case series

S Dureja, P Thakral, V Pant, I Sen - Indian Journal of Nuclear …, 2017 - journals.lww.com
Ga-68 labeled prostate-specific membrane antigen (PSMA) whole body PET/CT scan is a
novel upcoming modality for the evaluation of prostate cancer. We present three cases of …