The glymphatic system, that is aquaporin 4 (AQP4) facilitated exchange of CSF with interstitial
fluid (ISF), may provide a clearance pathway for protein species such as amyloid-β and tau…

Increased hyperphosphorylated tau and the formation of intracellular neurofibrillary tangles
are associated with the loss of neurons and cognitive decline in Alzheimer's disease, and …

As the number of people diagnosed with Alzheimer's disease (AD) reaches epidemic
proportions, there is an urgent need to develop effective treatment strategies to tackle the social …

Magnetic resonance imaging (MRI) has become a popular modality in guiding minimally
invasive thermal therapies, due to its advanced, nonionizing, imaging capabilities and its ability …

The in-vivo mechanical response of neural tissue during impact loading of the head is
simulated using geometrically accurate finite element (FE) head models. However, current FE …

With increasingly large numbers of mouse models of human disease dedicated to MRI studies,
compromises between in vivo and ex vivo MRI must be fully understood in order to inform …

Mouse models of Alzheimer's disease have served as valuable tools for investigating pathogenic
mechanisms relating to neurodegeneration, including tau-mediated and neurofibrillary …

Purpose To assess current perceptions, practices and education needs pertaining to artificial
intelligence (AI) in the medical physics field. Methods A web-based survey was distributed …

Vascular abnormalities are a key feature of Alzheimer's disease (AD). Imaging of cerebral
vascular reactivity (CVR) is a powerful tool to investigate vascular health in clinical populations …

Take a right circular solid rubber cylinder and twist it to produce a rotation of angle θ between
the upper and lower faces, see Fig. 1. Do you expect the cylinder to (a) shorten,(b) keep its …