Many solid tumors contain an overabundance of phospholipid ethers relative to normal cells.
Capitalizing on this difference, we created cancer-targeted alkylphosphocholine (APC) …

In this experiment students prepare nickel nanowires using a template synthesis technique
and characterize their properties. Electrodeposition of nickel to fill the 200-nm diameter pores …

BACKGROUND: 5-Aminolevulinic acid (5-ALA)-induced tumor fluorescence aids brain
tumor resections but is not approved for routine use in the United States. We developed and …

Aberrations in the phosphoinositide 3-kinase (PI3K) signaling pathway play a key role in the
pathogenesis of numerous cancers by altering cellular growth, metabolism, proliferation, …

Extracellular vesicles (EVs) have garnered increasing interest as delivery vehicles for
multiple classes of therapeutics based on their role as mediators in an important, natural …

In animal models of cancer, oncologic imaging has evolved from a simple assessment of
tumor location and size to sophisticated multimodality exploration of molecular, physiologic, …

Fully automated radiosynthesizers are continuing to be developed to meet the growing need
for the reliable production of PET tracers made under current good manufacturing practice …

The human brain and skull are three dimensional (3D) anatomical structures with complex
surfaces. However, medical images are often two dimensional (2D) and provide incomplete …

The phosphatidylinositide-3-kinase (PI3K) signaling pathway is critical for multiple cellular
functions including metabolism, proliferation, angiogenesis, and apoptosis, and is the most …

Positron emission tomography (PET) phantoms are used to calibrate PET scanners so that
inter-scanner and inter-isotope comparison can be made between PET datasets. Hot rod …