Background The oligometastatic paradigm suggests that some patients with a limited number
of metastases might be cured if all lesions are eradicated. Evidence from randomised …

PURPOSE The oligometastatic paradigm hypothesizes that patients with a limited number of
metastases may achieve long-term disease control, or even cure, if all sites of disease can …

Background Whole breast irradiation delivered once per day over 3–5 weeks after breast
conserving surgery reduces local recurrence with good cosmetic results. Accelerated partial …

BACKGROUND AND PURPOSE: To perform a systematic review of the predictive ability of
various dose–volume histogram (DVH) parameters (V dose , mean lung dose (MLD), and …

Importance Optimizing radiation therapy techniques for localized prostate cancer can affect
patient outcomes. Dose escalation improves biochemical control, but no prior trials were …

Background Dravet syndrome is a rare, treatment-resistant developmental epileptic
encephalopathy characterised by multiple types of frequent, disabling seizures. Fenfluramine has …

The vast area of swamp and wetlands of the Southern Sudan, the Sudd, absorbs and dissipates
by evaporation about half the inflow from the upper catchment of the White Nile. Ways …

Importance Fenfluramine treatment may reduce monthly convulsive seizure frequency in
patients with Dravet syndrome who have poor seizure control with their current stiripentol-…

Background. No licensed cholera vaccine is presently available in the United States.
Cholera vaccines available in other countries require 2 spaced doses. A single-dose cholera …

Over the past decade, there has been an increasing use of radiotherapy (RT) for the treatment
of liver metastases. Most often, ablative doses are delivered to focal liver metastases with …