User profiles for Justin Jacob

Justin T. Jacob, Ph.D.

- Verified email at dc.gov - Cited by 662

Justin Jacob,PhD

- Verified email at stanford.edu - Cited by 124

[HTML][HTML] Regeneration or repair? The role of alveolar epithelial cells in the pathogenesis of idiopathic pulmonary fibrosis (IPF)

P Confalonieri, MC Volpe, J Jacob, S Maiocchi… - Cells, 2022 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease (ILD)
with unknown etiology in which gradual fibrotic scarring of the lungs leads to usual interstitial …

Types I and II keratin intermediate filaments

JT Jacob, PA Coulombe, R Kwan… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Keratins—types I and II—are the intermediate-filament-forming proteins expressed in epithelial
cells. They are encoded by 54 evolutionarily conserved genes (28 type I, 26 type II) and …

Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes

RP Hobbs, DJ DePianto, JT Jacob, MC Han… - Nature …, 2015 - nature.com
Expression of the intermediate filament protein keratin 17 (K17) is robustly upregulated in
inflammatory skin diseases and in many tumors originating in stratified and pseudostratified …

[HTML][HTML] Meiosis-Specific Cohesin Component, Stag3 Is Essential for Maintaining Centromere Chromatid Cohesion, and Required for DNA Repair and Synapsis …

J Hopkins, G Hwang, J Jacob, N Sapp, R Bedigian… - PLoS …, 2014 - journals.plos.org
Cohesins are important for chromosome structure and chromosome segregation during
mitosis and meiosis. Cohesins are composed of two structural maintenance of chromosomes (…

Preparation, characterization and evaluation of a biopolymeric gold nanocomposite with antimicrobial activity

…, SSL Sobhana, JP Jacob… - Biotechnology and …, 2010 - Wiley Online Library
The present study describes the antimicrobial activity of C‐AuNp‐Amp (chitosan‐capped
gold nanoparticles coupled with ampicillin). C‐AuNp‐Amp was synthesized using the wet …

[PDF][PDF] Keratins are going nuclear

RP Hobbs, JT Jacob, PA Coulombe - Developmental cell, 2016 - cell.com
Previously thought to reside exclusively in the cytoplasm, the cytoskeletal protein keratin 17 (K17)
has been recently identified inside the nucleus of tumor epithelial cells with a direct …

A role for keratin 17 during DNA damage response and tumor initiation

RR Nair, J Hsu, JT Jacob, CM Pineda… - Proceedings of the …, 2021 - National Acad Sciences
High levels of the intermediate filament protein keratin 17 (K17) are associated with poor
prognoses for several human carcinomas. Studies in mouse models have shown that K17 …

Bone mineral density: clinical relevance and quantitative assessment

…, T Chukir, PJ Smith, JT Jacob… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Bone mineral density (BMD) measurement by dual-energy x-ray absorptiometry (DXA) is an
internationally accepted standard-of-care screening tool used to assess fragility-fracture risk. …

Repeated six-minute walk tests for outcome measurement and exercise prescription in outpatient cardiac rehabilitation: a longitudinal study

RN Bellet, RL Francis, JS Jacob, KM Healy… - Archives of physical …, 2011 - Elsevier
Bellet RN, Francis RL, Jacob JS, Healy KM, Bartlett HJ, Adams L, Morris NR. Repeated six-minute
walk tests for outcome measurement and exercise prescription in outpatient cardiac …

Senescent chondrogenic progenitor cells derived from articular cartilage of knee osteoarthritis patients contributes to senescence-associated secretory phenotype via …

J Jacob, A Aggarwal, A Aggarwal, S Bhattacharyya… - Acta …, 2022 - Elsevier
Justin Jacob and Anjali Aggarwal conceptualized this study. Justin Jacob collected tissue
samples, carried out all the experiments, acquired the data and prepared the manuscript. …