[HTML][HTML] Characterisation and germline transmission of cultured avian primordial germ cells
J Macdonald, JD Glover, L Taylor, HM Sang… - PloS one, 2010 - journals.plos.org
Background Avian primordial germ cells (PGCs) have significant potential to be used as a
cell-based system for the study and preservation of avian germplasm, and the genetic …
cell-based system for the study and preservation of avian germplasm, and the genetic …
Efficient genetic modification and germ-line transmission of primordial germ cells using piggyBac and Tol2 transposons
J Macdonald, L Taylor, A Sherman… - Proceedings of the …, 2012 - National Acad Sciences
The derivation of germ-line competent avian primordial germ cells establishes a cell-based
model system for the investigation of germ cell differentiation and the production of …
model system for the investigation of germ cell differentiation and the production of …
Prolonged exposure to acetaminophen reduces testosterone production by the human fetal testis in a xenograft model
S van den Driesche, J Macdonald… - Science translational …, 2015 - science.org
Most common male reproductive disorders are linked to lower testosterone exposure in fetal
life, although the factors responsible for suppressing fetal testosterone remain largely …
life, although the factors responsible for suppressing fetal testosterone remain largely …
Effects of exposure to acetaminophen and ibuprofen on fetal germ cell development in both sexes in rodent and human using multiple experimental systems
…, RA Anderson, J Macdonald… - Environmental …, 2018 - ehp.niehs.nih.gov
Background: Analgesic exposure during pregnancy may affect aspects of fetal gonadal
development that are targeted by endocrine disruptors. Objectives: We investigated whether …
development that are targeted by endocrine disruptors. Objectives: We investigated whether …
[PDF][PDF] Nodal signaling regulates germ cell development and establishment of seminiferous cords in the human fetal testis
A Jørgensen, J Macdonald, JE Nielsen, KR Kilcoyne… - Cell Reports, 2018 - cell.com
Disruption of human fetal testis development is widely accepted to underlie testicular germ
cell cancer (TGCC) origin and additional disorders within testicular dysgenesis syndrome (…
cell cancer (TGCC) origin and additional disorders within testicular dysgenesis syndrome (…
[HTML][HTML] Intratubular germ cell neoplasia of the human testis: heterogeneous protein expression and relation to invasive potential
RT Mitchell, ME Camacho-Moll, J Macdonald… - Modern Pathology, 2014 - Elsevier
Testicular germ cell cancer develops from premalignant intratubular germ cell neoplasia,
unclassified cells that are believed to arise from failure of normal maturation of fetal germ cells …
unclassified cells that are believed to arise from failure of normal maturation of fetal germ cells …
Development of novel reagents to chicken FLT3, XCR1 and CSF2R for the identification and characterization of avian conventional dendritic cells
Z Wu, T Hu, C Chintoan‐Uta, J Macdonald… - …, 2022 - Wiley Online Library
Conventional dendritic cells (cDC) are bone marrow‐derived immune cells that play a central
role in linking innate and adaptive immunity. cDCs efficiently uptake, process and present …
role in linking innate and adaptive immunity. cDCs efficiently uptake, process and present …
[HTML][HTML] Development and function of chicken XCR1+ conventional dendritic cells
Z Wu, B Shih, J Macdonald, D Meunier… - Frontiers in …, 2023 - frontiersin.org
Conventional dendritic cells (cDCs) are antigen-presenting cells (APCs) that play a central
role in linking innate and adaptive immunity. cDCs have been well described in a number of …
role in linking innate and adaptive immunity. cDCs have been well described in a number of …
DMRT1 repression using a novel approach to genetic manipulation induces testicular dysgenesis in human fetal gonads
J Macdonald, KR Kilcoyne, RM Sharpe… - Human …, 2018 - academic.oup.com
STUDY QUESTION Does loss of DMRT1 in human fetal testis alter testicular development
and result in testicular dysgenesis? SUMMARY ANSWER DMRT1 repression in human fetal …
and result in testicular dysgenesis? SUMMARY ANSWER DMRT1 repression in human fetal …
Idiopathic hepatic uptake of 99mTc methylene diphosphonate: a case report
J MacDonald - Journal of Nuclear Medicine Technology, 2001 - Soc Nuclear Med
Objective:Two sequential 99m Tc methylene diphosphonate (MDP) scans were performed
on a 42-y-old woman with insulin-dependent diabetes mellitus, chronic right pyelonephritis …
on a 42-y-old woman with insulin-dependent diabetes mellitus, chronic right pyelonephritis …