Early prediction of response to chemotherapy and survival in malignant pleural mesothelioma using a novel semiautomated 3-dimensional volume-based analysis of …

…, MJ Byrne, AA van der Schaaf, JA Boucek… - Journal of Nuclear …, 2007 - Soc Nuclear Med
The aim of chemotherapy for mesothelioma is to palliate symptoms and improve survival.
Measuring response using CT is challenging because of the circumferential tumor growth …

[HTML][HTML] Post-radioembolization yttrium-90 PET/CT-part 2: dose-response and tumor predictive dosimetry for resin microspheres

…, J Yan, DW Townsend, CA Budgeon, JA Boucek… - EJNMMI research, 2013 - Springer
Background Coincidence imaging of low-abundance yttrium-90 ( 90 Y) internal pair
production by positron emission tomography with integrated computed tomography (PET/CT) …

Validation of prospective whole-body bone marrow dosimetry by SPECT/CT multimodality imaging in 131I-anti-CD20 rituximab radioimmunotherapy of non-Hodgkin's …

JA Boucek, JH Turner - European journal of nuclear medicine and …, 2005 - Springer
Purpose Radioimmunotherapy (RIT) for relapsed non-Hodgkin’s lymphoma is emerging as
a promising treatment strategy. Myelosuppression is the dose-limiting toxicity and may be …

Personalized Dosimetry of 131I-Rituximab Radioimmunotherapy of Non-Hodgkin Lymphoma Defined by Pharmacokinetics in Bone Marrow and Blood

JA Boucek, JH Turner - Cancer Biotherapy and …, 2014 - liebertpub.com
Purpose: To report a comparison of SPECT/CT technique with standard blood-based
dosimetry methodology in a cohort of non-Hodgkin lymphoma (NHL) patients treated with 131 I-…

A gelatin liver phantom of suspended 90Y resin microspheres to simulate the physiologic microsphere biodistribution of a postradioembolization liver

…, SR Culleton, RJ Francis, JA Boucek - Journal of nuclear …, 2014 - Soc Nuclear Med
For phantom studies involving 90 Y PET/CT, homogeneous solutions of 90 Y, for example,
90 Y citrate, are commonly used. However, the microsphere biodistribution of a …

[HTML][HTML] The head and neck squamous cell carcinoma microenvironment as a potential target for cancer therapy

J Plzák, J Bouček, V Bandúrová, M Kolář, M Hradilová… - Cancers, 2019 - mdpi.com
Similarly to other types of malignant tumours, the incidence of head and neck cancer is
increasing globally. It is frequently associated with smoking and alcohol abuse, and in a broader …

Regulatory T cells and their prognostic value for patients with squamous cell carcinoma of the head and neck

J Boucek, T Mrkvan, M Chovanec… - Journal of cellular …, 2010 - Wiley Online Library
Regulatory T cells (Treg) are important regulators of anti‐cancer immune responses, and an
increase in Treg frequency was observed in the blood of cancer patients. Blood samples …

A novel prognostic model for malignant mesothelioma incorporating quantitative FDG-PET imaging with clinical parameters

…, MJ Millward, AA van der Schaaf, J Boucek… - Clinical Cancer …, 2010 - AACR
Jan Boucek; Jan Boucek … van der Schaaf, Jan Boucek, Arthur W. Musk, Melanie J.
McCoy, Amanda Segal, Peter Robins, Michael J. …

[HTML][HTML] Synthesis of human amyloid restricted to liver results in an Alzheimer disease–like neurodegenerative phenotype

…, L Morandeau, J Gauntlett, C Leatherday, J Boucek… - PLoS …, 2021 - journals.plos.org
Several lines of study suggest that peripheral metabolism of amyloid beta (Aß) is associated
with risk for Alzheimer disease (AD). In blood, greater than 90% of Aß is complexed as an …

[HTML][HTML] The role of narrow band imaging in the detection of recurrent laryngeal and hypopharyngeal cancer after curative radiotherapy

M Zabrodsky, P Lukes, E Lukesova, J Boucek… - BioMed research …, 2014 - hindawi.com
Narrow band imaging is considered a significant improvement in the possibility of detecting
early mucosal lesion of the upper aerodigestive tract. Early detection of mucosal neoplastic …