Neuromyelitis optica (NMO) is an inflammatory CNS syndrome distinct from multiple
sclerosis (MS) that is associated with serum aquaporin-4 immunoglobulin G antibodies (AQP4-IgG). …

… where the first term describes hopping between nearestneighboring sites of the honeycomb
lattice, with hopping amplitude J, where FðtÞ ¼ F½cosðΩtÞex þ sinðΩtÞey reflects the …

Polycomb proteins form chromatin-modifying complexes that implement transcriptional silencing
in higher eukaryotes. Hundreds of genes are silenced by Polycomb proteins, including …

Background Nivolumab, a programmed death 1 (PD-1) checkpoint inhibitor, was associated
with encouraging overall survival in uncontrolled studies involving previously treated …

… In Simon's view, the key factor in natural and world economic … he would encounter, Simon
nevertheless wrote The Economics … We should also add, in honor of Simon, the courage to use …

Parkinson's disease (PD; OMIM #168600) is the second most common neurodegenerative
disorder in the Western world and presents as a progressive movement disorder. The …

Chronic infection with hepatitis C virus (HCV) affects 170 million people worldwide and is
the leading cause of cirrhosis in North America 1 . Although the recommended treatment for …

Ascertaining the impact of uncharacterized perturbations on the cell is a fundamental problem
in biology. Here, we describe how a single assay can be used to monitor hundreds of …

DNase I hypersensitive sites (DHSs) are markers of regulatory DNA and have underpinned
the discovery of all classes of cis-regulatory elements including enhancers, promoters, …

The accepted standard treatment of relapsing multiple sclerosis consists of medications for
disease symptoms, including treatment for acute exacerbations. However, currently there is …