Estimating kinetic parameters from dynamic contrast‐enhanced t1‐weighted MRI of a diffusable tracer: Standardized quantities and symbols

PS Tofts, G Brix, DL Buckley… - Journal of Magnetic …, 1999 - Wiley Online Library
We describe a standard set of quantity names and symbols related to the estimation of kinetic
parameters from dynamic contrast‐enhanced T 1 ‐weighted magnetic resonance imaging …

Quantification of regional cerebral blood flow and volume with dynamic susceptibility contrast-enhanced MR imaging.

KA Rempp, G Brix, F Wenz, CR Becker, F Gückel… - Radiology, 1994 - pubs.rsna.org
PURPOSE: Quantification of regional cerebral blood flow (rCBF) and volume (rCBV) with
dynamic magnetic resonance (MR) imaging. MATERIALS AND METHODS: After bolus …

Pharmacokinetic parameters in CNS Gd-DTPA enhanced MR imaging

G Brix, W Semmler, R Port, LR Schad… - Journal of computer …, 1991 - journals.lww.com
Dynamic MR imaging can be used to study tissue perfusion and vascular permeability. In the
present article a procedure for dynamic MR is presented, which (a) accurately resolves the …

Radiation exposure of patients undergoing whole-body dual-modality 18F-FDG PET/CT examinations

G Brix, U Lechel, G Glatting, SI Ziegler… - Journal of Nuclear …, 2005 - Soc Nuclear Med
We investigated radiation exposure of patients undergoing whole-body 18 F-FDG PET/CT
examinations at 4 hospitals equipped with different tomographs. Methods: Patient doses were …

[PDF][PDF] Performance evaluation of a whole-body PET scanner using the NEMA protocol

G Brix, J Zaers, LE Adam, ME Bellemann… - Journal of Nuclear …, 1997 - Soc Nuclear Med
The scanner consists of four rings of 72 bismuth germanate block detectors each, covering
an axial field of view of 15.5 cm with a patient port of 56.2 cm. A single block detector is …

Microcirculation and microvasculature in breast tumors: pharmacokinetic analysis of dynamic MR image series

G Brix, F Kiessling, R Lucht, S Darai… - … in Medicine: An …, 2004 - Wiley Online Library
The purpose of this study was to quantify microcirculation and microvasculature in breast
lesions by pharmacokinetic analysis of Gd‐DTPA‐enhanced MRI series. Strongly T 1 ‐…

Pharmacokinetic mapping of the breast: a new method for dynamic MR mammography

U Hoffmann, G Brix, MV Knopp, T Heβ… - Magnetic resonance …, 1995 - Wiley Online Library
A dynamic contrast‐enhanced MRI technique for whole breast examinations is presented.
The fast kinetics of tissue response during and after constant‐rate intravenous infusion of …

Regorafenib inhibits growth, angiogenesis, and metastasis in a highly aggressive, orthotopic colon cancer model

L Abou-Elkacem, S Arns, G Brix, F Gremse… - Molecular cancer …, 2013 - AACR
The combination of target-specific drugs like bevacizumab with chemotherapeutics has
improved treatment efficacy in advanced colorectal cancer (CRC). However, the clinical …

Regional blood flow, capillary permeability, and compartmental volumes: measurement with dynamic CT—initial experience

G Brix, ML Bahner, U Hoffmann, A Horvath… - Radiology, 1999 - pubs.rsna.org
Sequential computed tomographic scanning was performed in patients with neck tumors
after contrast material administration. For data analysis, a pharmacokinetic two-compartment …

Dynamic contrast‐enhanced MRI using Gd‐DTPA: interindividual variability of the arterial input function and consequences for the assessment of kinetics in tumors

RE Port, MV Knopp, G Brix - … in Medicine: An Official Journal of …, 2001 - Wiley Online Library
Gd‐DTPA kinetics in arterial blood was investigated by dynamic MRI in 47 patients with
malignant and benign mammary tumors. Signal enhancement was monitored for 10 min after the …