Cerebrovascular accidents are one of the life‐threatening complications of diabetic ketoacidosis
(DKA) in children and adolescents. Our objective was to evaluate the effect of DKA and …

Elevated plasma levels of C-reactive protein (CRP) and IL-6 have been reported to be
sensitive indicators of infection in adults with diabetic ketoacidosis (DKA). However, both CRP …

OBJECTIVES:: Diabetic ketoacidosis (DKA) represents a metabolic stress whose treatment
induces a systemic proinflammatory cytokine profile and accentuates life-threatening acute …

Objective: To evaluate the effects of diabetic ketoacidosis (DKA) on neurocognitive functions
in children and adolescents presenting with newonset type 1 diabetes. Methods: Newly …

Radiologic and neuropsychologic studies suggest that diabetes mellitus causes structural
changes in the brain and adversely effects cognitive development. Experimental animal …

The acute complications of diabetic ketoacidosis in children and adolescents are well recognized
but not completely understood. Clinical studies have focused primarily on brain edema…

It has been hypothesized that ketone bodies cause activation of brain endothelial cells and
that this is a factor in the intracerebral crises of diabetic ketoacidosis (DKA). In this study we …

Cerebral edema is the most significant complication in children with diabetic ketoacidosis (DKA).
Our goal was to study whether subclinical cerebral edema was preferentially vasogenic …

Diastolic dysfunction suggestive of diabetic cardiomyopathy is established in children with
T1DM, but its pathogenesis is not well understood. We studied the relationships of systemic …

OBJECTIVES: Highly reactive dicarbonyl compounds are known to be increased by
hyperglycemia, ketone bodies and lipid peroxidation. This study was carried out to investigate the …