User profiles for Giuseppe Esposito

Giuseppe Esposito

- Verified email at uniroma1.it - Cited by 7831

Giuseppe Esposito

- Verified email at irpi.cnr.it - Cited by 775

Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia

…, RS Miletich, PD Kohn, G Esposito… - Nature …, 2002 - nature.com
Both dopaminergic neurotransmission and prefrontal cortex (PFC) function are known to be
abnormal in schizophrenia. To test the hypothesis that these phenomena are related, we …

[HTML][HTML] The challenge of unprecedented floods and droughts in risk management

…, MC De Ruiter, C Delus, M Erfurt, G Esposito… - Nature, 2022 - nature.com
Risk management has reduced vulnerability to floods and droughts globally 1 , 2 , yet their
impacts are still increasing 3 . An improved understanding of the causes of changing impacts …

[HTML][HTML] Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement

G Esposito, C Scuderi, M Valenza, GI Togna, V Latina… - PloS one, 2011 - journals.plos.org
Peroxisome proliferator-activated receptor-γ (PPARγ) has been reported to be involved in
the etiology of pathological features of Alzheimer's disease (AD). Cannabidiol (CBD), a …

Neuroprotective effect of cannabidiol, a non‐psychoactive component from Cannabis sativa, on β‐amyloid‐induced toxicity in PC12 cells

T Iuvone, G Esposito, R Esposito… - Journal of …, 2004 - Wiley Online Library
Alzheimer's disease is widely held to be associated with oxidative stress due, in part, to the
membrane action of β‐amyloid peptide aggregates. Here, we studied the effect of cannabidiol…

Modulation of cognition-specific cortical activity by gonadal steroids: a positron-emission tomography study in women

…, JD Van Horn, G Esposito… - Proceedings of the …, 1997 - National Acad Sciences
There is considerable evidence from animal studies that gonadal steroid hormones modulate
neuronal activity and affect behavior. To study this in humans directly, we used H 2 15 O …

A comparison of rCBF patterns during letter and semantic fluency.

…, DR Weinberger, JM Gold, G Esposito… - …, 2000 - psycnet.apa.org
To evaluate the functional neuroanatomies underlying letter and category fluency, 18 normal
controls were studied with oxygen-15 water regional cerebral blood flow positron emission …

Cannabidiol in vivo blunts β‐amyloid induced neuroinflammation by suppressing IL‐1β and iNOS expression

G Esposito, C Scuderi, C Savani… - British journal of …, 2007 - Wiley Online Library
Background and purpose: Pharmacological inhibition of beta‐amyloid (Aβ) induced reactive
gliosis may represent a novel rationale to develop drugs able to blunt neuronal damage …

H215O PET validation of steady‐state arterial spin tagging cerebral blood flow measurements in humans

…, KF Berman, T Ellmore, G Esposito… - … in Medicine: An …, 2000 - Wiley Online Library
Steady‐state arterial spin tagging approaches can provide quantitative images of CBF, but
have not been validated in humans. The work presented here compared CBF values …

The spice sage and its active ingredient rosmarinic acid protect PC12 cells from amyloid-β peptide-induced neurotoxicity

T Iuvone, D De Filippis, G Esposito, A D'Amico… - … of Pharmacology and …, 2006 - ASPET
Traditional use and clinical reports suggest that the culinary herb sage (Salvia officinalis)
may be effective for patients with mild to moderate Alzheimer's disease (AD). In this study, we …

Cannabinoid CB1‐receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation

…, L Pinto, T Iuvone, G Esposito… - British journal of …, 2001 - Wiley Online Library
We have studied the effect of cannabinoid agonists (CP 55,940 and cannabinol) on intestinal
motility in a model of intestinal inflammation (induced by oral croton oil in mice) and …