Osteoblasts and endothelium constitute functional niches that support haematopoietic stem
cells in mammalian bone marrow 1 , 2 , 3 . Adult bone marrow also contains adipocytes, the …

Although 18 F-labeled NaF was the first widely used agent for skeletal scintigraphy, it
quickly fell into disuse after the introduction of 99m Tc-labeled bone-imaging agents. Recent …

Osteosarcoma is the most common primary malignant tumor of bone. Analysis of familial
cancer syndromes and sporadic cases has strongly implicated both p53 and pRb in its …

Data acquisition is substantially different in PET than it is in planar nuclear medicine and
SPECT. There is an entirely different set of definitions and considerations. The objective of this …

Dexmedetomidine is a selective α 2-agonist approved for sedation of critically ill patients.
There is little information on the effects of dexmedetomidine on cerebral blood flow (CBF) or …

Phagocytic cell NADPH oxidase (NOX) generates reactive oxygen species (ROS) as part of
innate immunity. Unfortunately, ischemia can also induce this pathway and inflict damage on …

The value of pediatric nuclear medicine is well established. Pediatric patients are referred to
nuclear medicine from nearly all pediatric specialties including urology, oncology, …

Background A phase II study of bevacizumab (BVZ) plus irinotecan (CPT-11) was conducted
in children with recurrent low-grade glioma to measure sustained response and/or stable …

Effective dose was introduced by the ICRP for the single, over-arching purpose of setting limits
for radiation protection. Effective dose is a derived quantity or mathematical construct and …

Purpose The purpose of this study was to evaluate the variability in quantitation of positron
emission tomography (PET) data acquired within the context of a multicenter consortium. …