M odern medical practice requires rapid decisions. Patients must be triaged faster, treated
more expeditiously, and discharged earlier. Diagnostic tests used to evaluate patients with …

Background In this work, we report a novel targetable ultrasonic contrast agent with the potential
to noninvasively define and localize myriad pathological tissues for diagnosis or therapy…

Before molecular imaging with MRI can be applied clinically, certain problems, such as the
potential sparseness of molecular epitopes on targeted cell surfaces, and the relative …

Background— Restenosis is a serious complication of coronary angioplasty that involves the
proliferation and migration of vascular smooth muscle cells (VSMCs) from the media to the …

Recently, we have identified the dramatic depletion of cardiolipin (CL) in diabetic myocardium
6 weeks after streptozotocin (STZ) injection that was accompanied by increases in …

Criteria for the retrospective diagnosis of acute myocardial infarction rely heavily on
increases in lactate dehydrogenase (LD) isoenzymes. However, increases of LD isoenzyme …

A biodegradable positron-emitting dendritic nanoprobe targeted at α v β 3 integrin, a biological
marker known to modulate angiogenesis, was developed for the noninvasive imaging of …

Diabetic cardiomyopathy is characterized by excessive utilization of fatty acid substrate,
diminished glucose transport, and mitochondrial dysfunction. However, the chemical …

Accurate delineation of the volumetric motion of the left ventricle (LV) of the heart from tagged
magnetic resonance imaging (MRI) is an important area of research. The authors have …

Diabetic cardiomyopathy is the result of maladaptive changes in energy homeostasis.
However, the biochemical mechanisms underlying dysfunctional lipid metabolism in diabetic …