Copper-64 (T 1 2 = 12.7 h ) is an intermediate-lived positron-emitting radionuclide that is a
useful radiotracer for positron emission tomography (PET) as well as a promising …

The use of radionuclides in medicine is based largely on the discoveries of two critical concepts,
the “tracer principle” and the “magic bullet”. In 1913, George de Hevesy developed the …

Systemic delivery of therapeutic agents to solid tumors is hindered by vascular and
interstitial barriers. We hypothesized that prostate tumor specific epigallocatechin-gallate (EGCg) …

Over recent years, within the community of radiopharmaceutical sciences, there has been an
increased incidence of incorrect usage of established scientific terms and conventions, and …

With Au nanocages as an example, we recently demonstrated that radioactive 198 Au could
be incorporated into the crystal lattice of Au nanostructures for simple and reliable …

Development of cancer receptor-specific gold nanoparticles will allow efficient targeting/optimum
retention of engineered gold nanoparticles within tumors and thus provide synergistic …

Approximately 192,280 men are diagnosed with prostate cancer every year, resulting in loss
of life for 27,360 men in the United States and 288,000 men worldwide if not treated in its …

Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) is an aberrant fusion gene product
expressed in a subset of cases of anaplastic large cell lymphoma (ALCL). It has been …

Previously we described the high yield production of 64 Cu using a target system designed
specifically for low energy, biomedical cyclotrons. In this study, the use of this target system …

Cerenkov luminescence imaging based on light emission from the decay of radionuclides has
recently drawn great interest in molecular imaging. In this paper, we report for the first time …