Background: Butyrylcholinesterase (BChE), also known as the “pseudo” or “non-neuronal”
cholinesterase, is traditionally thought to have a restricted CNS distribution and to play little, if …

Cells of the craniofacial skeleton are derived from a common mesenchymal progenitor. The
regulatory factors that control their differentiation into various cell lineages are unknown. To …

The conformation-dependent antibodies Tau-66 and Alz-50 recognize discontinuous epitopes
on the tau molecule (residues 155–244 & 305–314 and 5–15 & 312–322, respectively), …

Background Mutations in the tau gene have been reported in families with frontotemporal
dementia (FTD) linked to chromosome 17. It remains uncertain how commonly such mutations …

Background Headache may be the presenting complaint of serious diagnoses such as
meningitis, brain tumor, or shunt malfunction, yet no previous studies have examined the …

The authors review the relationship of repetitive behaviors to frontal lobe degenerations and
report the repetitive and compulsive behaviors, radiologic imaging findings, and …

The meperidine analogue derivative 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
induces nigrostriatal fiber damage and severe parkinsonism in humans and animals. MPTP-…

In a national prospective registry, we previously studied the impact of 18 F-sodium fluoride
PET (NaF PET) on the intended management of cancer patients with osseous metastases. …

The isolation, structure determination, and total synthesis of Fluoro Nissl Green, a novel
RNA-binding fluorochrome, are reported. Initially obtained in only one part per 105, via a …

Objectives: To describe the lifetime outcomes and economic implications of combinatorial
pharmacogenomic (CPGx) testing versus treatment as usual (TAU) psychopharmacologic …