Our understanding of the cellular implementation of systems-level neural processes like
action, thought and emotion has been limited by the availability of tools to interrogate specific …

Background The accuracy of multidetector computed tomographic angiography (CTA) for
the diagnosis of acute pulmonary embolism has not been determined conclusively. Methods …

In glioblastoma-derived cell lines, PTEN does not significantly alter apoptotic sensitivity or
cause complete inhibition of DNA synthesis. However, in these cell lines PTEN regulates …

For studying the function of specific neurons in their native circuitry, it is desired to precisely
control their activity. This often requires dissection to allow accurate electrical stimulation [1] …

Spatial and temporal control over chemical and biological processes plays a key role in life,
where the whole is often much more than the sum of its parts. Quite trivially, the molecules of …

We measured cardiac performance sequentially, using quantitative radionuclide angiocardiography
to estimate left ventricular ejection fraction in 55 patients receiving doxorubicin for …

Genetically encoded calcium indicators (GECIs) are powerful tools for systems neuroscience.
Here we describe red, single-wavelength GECIs, “RCaMPs,” engineered from circular …

(CT) angiography in the diagnosis of pulmonary embolism (PE) has dramatically increased
as a consequence of major advances in CT technology. The question now no longer …

BACKGROUND: Selection of patients for diagnostic tests for acute pulmonary embolism
requires recognition of the possibility of pulmonary embolism on the basis of the clinical …

Background: The accuracy of gadolinium-enhanced magnetic resonance pulmonary
angiography and magnetic resonance venography for diagnosing pulmonary embolism has not …