Electron spin resonance spectroscopy (ESR) of the nitroxide labelled fatty acid probes (5-,
16-doxyl stearic acid) was used to monitor the micelle microviscosity of three surfactants at …

Purpose Loss of brain synapses is an early pathological feature of Alzheimer’s disease. The
current study assessed synaptic loss in vivo with positron emission tomography and an 18F-…

Background Kinetic modeling of physiological function using imaging techniques requires
the accurate measurement of the time-activity curve of the tracer in plasma, known as the …

Synaptic vesicle protein 2 isoforms are critical for proper nervous system function and are
involved in vesicle trafficking. The synaptic vesicle protein 2A (SV2A) isoform has been …

Background Four state-of-the-art single-photon emission computed tomography-computed
tomography (SPECT-CT) systems, namely Philips Brightview, General Electric Discovery NM/…

Introduction Brain distribution of synaptic vesicle protein 2A was measured with fluorine‐18
UCB‐H ([ 18 F]UCB‐H) and positron emission tomography (PET). Methods Images of …

For many years the laboratory mouse has been used as the standard model for in vivo oncology
research, particularly in the development of novel PET tracers, but the growth of tumors …

The purpose of this exploratory research is to provide data on synaptopathy in the behavioral
variant of frontotemporal dementia (bvFTD). Twelve patients with probable bvFTD were …

Electron spin resonance (ESR) spectroscopy with nitroxide spin probes was used as a
method to probe the liposome microenvironments. The effective microviscosities have been …

Purpose [ 18 F]UCB-H is a novel radiotracer with a high affinity for synaptic vesicle
glycoprotein 2A (SV2A), a protein expressed in synaptic vesicles. SV2A is the binding site of …