Importance Midlife vascular risk factors have been associated with late-life dementia. Whether
these risk factors directly contribute to brain amyloid deposition is less well understood. …

Tissue growth and function depend on vascularization, and vascular insufficiency or excess
exacerbates many human diseases. Identification of the biological processes involved in …

Stem cells ensure tissue regeneration, while overgrowth of adipogenic cells may compromise
organ recovery and impair function. In myopathies and muscle atrophy associated with …

Introduction Fibrosis, or scar formation, is a pathological condition characterized by excessive
production and accumulation of collagen, loss of tissue architecture, and organ failure in …

Perivascular multipotent cells, pericytes, contribute to the generation and repair of various
tissues in response to injury. They are heterogeneous in their morphology, distribution, origin …

Neural progenitor cells have been proposed as a therapy for central nervous system disorders,
including neurodegenerative diseases and trauma injuries, however their accessibility is …

In older adults, changes in skeletal muscle composition are associated with increased
fibrosis, loss of mass, and decreased force, which can lead to dependency, morbidity, and …

There is currently no established therapy to treat or prevent Alzheimer’s disease. The ketogenic
diet supplies an alternative cerebral metabolic fuel, with potential neuroprotective effects…

We have found that binding sites for interleukin-13. ( IL13) are overexpressed in a vast
majority of high-grade astrocytomas. (HGAs). These binding sites for IL-13 are distinct from the …

Objective: To evaluate differences in amyloid deposition in a community-based cohort without
dementia by age, sex, race, education, and APOE ε4 allele status. Methods: Recruited …