Ga-67 scintigraphy after bone marrow harvest. Significance of "sacroiliac" asymmetry in the lymphoma patient

Clin Nucl Med. 1993 Feb;18(2):126-9. doi: 10.1097/00003072-199302000-00008.

Abstract

The importance of recognizing asymmetric Ga-67 citrate uptake in the sacroiliac region after bone marrow harvest and transplant is discussed in a case of non-Hodgkin's lymphoma. The patient underwent chemotherapy, irradiation, and autologous bone marrow transplant for stage IV disease. Ga-67 scintigraphy revealed sacroiliac asymmetry suggesting medial iliac reparative changes after bone marrow harvest. Iliac bone marrow biopsy showed no evidence of infection or of recurrent tumor. Subsequent follow-up imaging and open biopsy demonstrated lymphomatous invasion of adjacent soft tissue where initial findings were thought to represent benign, postharvest changes.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bone Marrow Transplantation*
  • Female
  • Gallium Radioisotopes* / pharmacokinetics
  • Humans
  • Ilium / diagnostic imaging*
  • Ilium / metabolism
  • Lymphoma, Large B-Cell, Diffuse / diagnostic imaging*
  • Lymphoma, Large B-Cell, Diffuse / pathology
  • Lymphoma, Large B-Cell, Diffuse / therapy
  • Neoplasm Invasiveness
  • Radionuclide Imaging
  • Sacrum / diagnostic imaging*
  • Sacrum / metabolism
  • Transplantation, Autologous

Substances

  • Gallium Radioisotopes