Osteoblastoma in the nasal cavity: F-18 FDG PET/CT and Tc-99m MDP 3-phase bone scan findings with pathologic correlation

Clin Nucl Med. 2011 Mar;36(3):214-7. doi: 10.1097/RLU.0b013e318208f2f9.

Abstract

A benign osteoblastoma of the nasal cavity is very rare. A 57-year-old woman, who had a radical hysterectomy for carcinoma of the uterine cervix 5 years ago, underwent F-18 FDG PET/CT. An expansile bone tumor with high glucose metabolism in the middle turbinate of the left nasal cavity was incidentally demonstrated. A subsequent Tc-99m methylene diphosphonate 3-phase bone scan revealed focal increased uptake of radionuclide in all 3 phases at the corresponding tumor. Histology confirmed a benign osteoblastoma that was composed of proliferating osteoblasts with woven bone spicules and rich vascular stroma. Scintigraphic findings, including F-18 FDG PET/CT and 3-phase bone scan, reflected the pathologic features well.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Middle Aged
  • Nasal Cavity / diagnostic imaging
  • Nasal Cavity / pathology*
  • Nose Neoplasms / diagnostic imaging*
  • Nose Neoplasms / pathology
  • Osteoblastoma / diagnostic imaging*
  • Osteoblastoma / pathology
  • Positron-Emission Tomography*
  • Technetium Tc 99m Medronate*
  • Tomography, X-Ray Computed*

Substances

  • Fluorodeoxyglucose F18
  • Technetium Tc 99m Medronate