Primary hyperparathyroidism

Otolaryngol Clin North Am. 2010 Apr;43(2):417-32, x. doi: 10.1016/j.otc.2010.01.009.

Abstract

Primary hyperparathyroidism is the most common cause of hypercalcemia in the outpatient setting. Phenotypically, it has evolved from a disease of overt symptomatology to one of vague complaints and biochemical diagnosis. Preoperative localization and intraoperative parathyroid hormone have revolutionized the surgical management of these patients. Minimally invasive operations are now common worldwide with low morbidity and high patient satisfaction.

Publication types

  • Review

MeSH terms

  • Diagnosis, Differential
  • Humans
  • Hypercalcemia / etiology*
  • Hypercalcemia / pathology
  • Hyperparathyroidism, Primary / diagnosis
  • Hyperparathyroidism, Primary / pathology
  • Hyperparathyroidism, Primary / surgery*
  • Image Processing, Computer-Assisted
  • Multiple Endocrine Neoplasia / diagnosis
  • Multiple Endocrine Neoplasia / pathology
  • Multiple Endocrine Neoplasia / surgery
  • Parathyroid Glands / pathology
  • Parathyroid Hormone / blood
  • Parathyroidectomy / methods
  • Postoperative Care
  • Radionuclide Imaging
  • Reoperation
  • Sensitivity and Specificity
  • Technetium Tc 99m Sestamibi
  • Tomography, Emission-Computed, Single-Photon
  • Tomography, X-Ray Computed
  • Ultrasonography

Substances

  • Parathyroid Hormone
  • Technetium Tc 99m Sestamibi