Treatment of refractory gastroparesis: gastric and jejunal tubes, botox, gastric electrical stimulation, and surgery

Gastrointest Endosc Clin N Am. 2009 Jan;19(1):73-82, vi. doi: 10.1016/j.giec.2008.12.010.

Abstract

Refractory gastroparesis is a challenging disorder for gastroenterologists, internists, surgeons, and all health care professionals involved in the care of these patients. It should be managed by a stepwise algorithm beginning with dietary modifications, then prokinetic and antiemetic medications, measures to control pain and address psychological issues, and endoscopic or surgical options in selected patients, including placement of feeding jejunostomy tubes.

Publication types

  • Review

MeSH terms

  • Algorithms
  • Anti-Dyskinesia Agents / therapeutic use*
  • Antiemetics / therapeutic use
  • Botulinum Toxins / therapeutic use*
  • Dopamine Antagonists / therapeutic use
  • Electric Stimulation Therapy*
  • Gastrectomy
  • Gastroparesis / diet therapy
  • Gastroparesis / drug therapy
  • Gastroparesis / surgery
  • Gastroparesis / therapy*
  • Humans
  • Jejunostomy
  • Nutritional Support* / instrumentation
  • Nutritional Support* / methods
  • Receptors, Gastrointestinal Hormone / agonists
  • Receptors, Neuropeptide / agonists
  • Recurrence
  • Stomach / innervation
  • Treatment Outcome

Substances

  • Anti-Dyskinesia Agents
  • Antiemetics
  • Dopamine Antagonists
  • Receptors, Gastrointestinal Hormone
  • Receptors, Neuropeptide
  • motilin receptor
  • Botulinum Toxins