Extra cardiac activity detected on myocardial perfusion scintigraphy after intra-arterial injection of 99mTc-MIBI

Clin Physiol Funct Imaging. 2008 Sep;28(5):285-6. doi: 10.1111/j.1475-097X.2008.00811.x. Epub 2008 Jun 5.

Abstract

Purpose: We present an unusual case of extra cardiac activity of 99mTc-MIBI in the left part of thorax and left upper extremity in a patient admitted for myocardial perfusion scintigraphy.

Methods: A standard 2-day protocol of 99mTc-MIBI perfusion scintigraphies starting day 1 with stress (dipyridamol) imaging and followed by rest imaging day 2 was performed.

Results: On day 2, when rest perfusion scintigraphy was carried out, extra cardiac activity was present in the left part of thorax and in the left upper extremity resulting in reduced accumulation of 99mTc-MIBI in cardiac tissue, prolongation of the study and interference of the extra cardiac activity with the cardiac image reconstructions. Whole-body scintigraphy disclosed an arterial flow distribution of activity to skeletal muscles in left shoulder and upper limb.

Conclusion: Accidentally injected radiotracer retrogradely into the arterial system resulted in an unusual extra cardiac activity interfering with later image processing.

Publication types

  • Case Reports

MeSH terms

  • Arm / diagnostic imaging
  • Exercise Test / methods
  • Humans
  • Male
  • Middle Aged
  • Muscle, Skeletal / diagnostic imaging
  • Myocardial Ischemia / diagnostic imaging*
  • Radiopharmaceuticals*
  • Shoulder / diagnostic imaging*
  • Technetium Tc 99m Sestamibi*
  • Thorax / diagnostic imaging*
  • Tomography, Emission-Computed, Single-Photon*

Substances

  • Radiopharmaceuticals
  • Technetium Tc 99m Sestamibi