Transplacental passage of non-ionic contrast agents resulting in fetal bowel opacification: a mimic of pneumoperitoneum in the newborn

Brook J Hill; Gaurav Saigal; Sandip Patel; George E Abdenour Jr

doi:10.1007/s00247-007-0422-4

Transplacental passage of non-ionic contrast agents resulting in fetal bowel opacification: a mimic of pneumoperitoneum in the newborn

Pediatr Radiol. 2007 Apr;37(4):396-8. doi: 10.1007/s00247-007-0422-4. Epub 2007 Feb 24.

Authors

Brook J Hill¹, Gaurav Saigal, Sandip Patel, George E Abdenour Jr

Affiliation

¹ Department of Radiology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

PMID: 17323055
DOI: 10.1007/s00247-007-0422-4

Abstract

Although animal studies suggest that non-ionic radiological contrast agents do not cross the placenta, case reports have documented transplacental passage of the non-ionic monomers iohexol and iopromide in humans. We report a case of presumed transplacental passage of the non-ionic monomer ioversol resulting in fetal bowel opacification and mimicking pneumoperitoneum.

Publication types

Case Reports

MeSH terms

Adult
Contrast Media / adverse effects*
Diagnosis, Differential
Dilatation, Pathologic / chemically induced
Female
Humans
Infant, Newborn
Intestinal Diseases / chemically induced*
Intestinal Diseases / diagnostic imaging
Male
Maternal-Fetal Exchange*
Pneumoperitoneum / diagnosis*
Pregnancy
Prenatal Exposure Delayed Effects / chemically induced*
Prenatal Exposure Delayed Effects / diagnostic imaging
Pulmonary Embolism / diagnostic imaging
Radiography
Rectum / diagnostic imaging
Triiodobenzoic Acids / adverse effects*
Vomiting / chemically induced

Substances

Contrast Media
Triiodobenzoic Acids
ioversol