18F FDG uptake in the large arteries: A correlation study with the atherogenic risk factors
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2020, PET ClinicsCitation Excerpt :Vascular FDG uptake in subclinical atherosclerosis, a chronic low-grade inflammatory disease, has long been documented through PET imaging in major vessels throughout the body, usually the aorta, carotids, and most recently the coronary arteries.11 FDG PET uptake was first incidentally noted in the vascular wall of large arteries, during an oncologic-indicated examination, and found that FDG vascular uptake correlated with CV risk factors.12 Validation of FDG PET as a marker of the inflammation in an atherosclerotic plaque originated from in vitro histology studies, including immunostaining for macrophages in endarterectomy samples from carotid plaques.13,14
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Copyright © 2002 Published by Elsevier Inc.