Letter from the Editors: SPECT V/Q Imaging of the Lungs

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    This agent has not been approved by the Food and Drug Administration for use in the United States. Reports comparing planar and SPECT V/Q studies reveal greater sensitivity for the tomographic procedure.38-40 One report showed an FN rate of 1.5% for SPECT.41

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    Prior to computed tomography (CT) becoming widely accessible in the 1990s, planar V/Q imaging was the only diagnostic test for suspected PE other than an invasive catheter pulmonary angiogram. Planar V/Q imaging has been available since the 1970s.8 Traditionally, the technique was reported in a probabilistic style in accordance with the Prospective Investigation of Pulmonary Embolism Diagnosis Study (PIOPED).5

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