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Gastric Emptying Rate of Solids in Patients with Nonulcer Dyspepsia

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Abstract

The underlying role of motility disorders anddelayed gastric emptying in nonulcer dyspepsia is stillquestioned. This study aimed to determine the role ofthe gastric emptying rate of solids in patients with nonulcer dyspepsia. By means of breathtest technology, gastric emptying results of 344consecutive patients with nonulcer dyspepsia werecompared with those of 70 normal healthy volunteers.Although gastric emptying was significantly delayed inpatients with nonulcer dyspepsia compared with normalvolunteers, there was a great overlap between the twogroups. Using 5-95% confidence intervals of the control group in about 30% of the patients withnonulcer dyspepsia gastric emptying was delayed. Nocorrelation was found between gastric emptying rate andage, weight, height, or sex of the subjects in both groups. These findings suggest that, apartfrom gastric emptying, other mechanisms are veryimportant in the etiology of nonulcerdyspepsia.

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Maes, B.D., Ghoos, Y.F., Hiele, M.I. et al. Gastric Emptying Rate of Solids in Patients with Nonulcer Dyspepsia. Dig Dis Sci 42, 1158–1162 (1997). https://doi.org/10.1023/A:1018881419010

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