Renal transplantationOverall outcomeDual Kidney Transplants From Very Old or Very Young Donors: Long-Term Outcomes and Complications
Section snippets
Patients and Methods
The medical records of all kidney transplant recipients transplanted in our center from July 2001 to December 2005 were reviewed. We performed DKT when the donor's estimated glomerular filtration rate (GFR) was <80 mL/min. If the donor GFR was >80 mL/min, a single kidney was transplanted. Seventy-four percent of DKTs were performed using imported organs after they were deemed unacceptable by their local center due to the donor's age. All dual kidneys were placed ipsilaterally (Fig 1) except in
Results
Donor and recipient demographics are shown in Table 1, Table 2, Table 3 Sixteen patients (mean age 68, range 60–78) received dual kidneys from VO (mean age 72, range 60–79) donors and 6 patients (mean age 47, range 27–72) were transplanted from VY (mean age 17 months, range 2–36 months) donors. All patients received antilymphocyte antibody induction therapy with Thymoglobulin (Genzyme, Cambridge, Mass, USA) at a total dose between 3 and 5 mg/kg. Recipients were maintained on a triple-drug
Discussion
Ojo showed that successful kidney transplantation prolongs patients' lives compared to maintenance dialysis.4 Although the greatest benefit appears to be provided by SCD kidneys, even recipients of ECD kidneys experience a survival advantage. The development of the DKT procedure increased the utilization rate of kidneys obtained from donors at the extremes of age that otherwise would have been discarded. The use of the DKT procedure was amply demonstrated in our study since 74% of our dual
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