Elsevier

Clinical Radiology

Volume 28, Issue 1, January–November 1977, Pages 97-105
Clinical Radiology

Problems and limitations of bone scanning with the 99Tcm-phosphates*

https://doi.org/10.1016/S0009-9260(77)80135-9Get rights and content

99Tcm-phosphate bone scans are being increasingly used in the detection of bony metatases. The sensitivity of the bone scan and the non-specific nature of the isotope image, when compared with radiographs, makes it important to be aware of the problems and limitations of the technique. This paper describes and illustrates some of the diagnostic problems encountered by the author over the past 3 years.

References (33)

  • CollinsD.H.

    Paget's disease of bone. Incidence and subclinical forms

    Lancet

    (1956)
  • FordhamE.W. et al.

    Radionuclide imaging of osseous trauma

    Seminars in Nuclear Medicine

    (1974)
  • BellE.G. et al.

    Local radiation damage to bone and marrow demonstrated by radioisotopic imaging

    Radiology

    (1969)
  • BergG.R. et al.

    99Tcm-diphosphonate concentration in primary breast carcinoma

    Radiology

    (1973)
  • BlauM. et al.

    Fluorine-18: a new isotope for bone scanning

    Journal of Nuclear Medicine

    (1962)
  • CastronovoF.P. et al.

    Effects of radiation therapy on bone lesions as measured by 99Tcm-diphosphonate

    Journal of Nuclear Medicine

    (1973)
  • CharkesN.D. et al.

    Early diagnosis of metastatic bone cancer by photoscanning with strontium-85

    Journal of Nuclear Medicine

    (1964)
  • CharkesN.D. et al.

    Detection of metastatic cancer to bone by scintiscanning with strontium-87m

    American Journal of Roentgenology, Radium Therapy and Nuclear Medicine

    (1964)
  • CharkesN.D. et al.

    A critical analysis of strontium bone scanning for detection of metastatic cancer

    American Journal of Roentgenology, Radium Therapy and Nuclear Medicine

    (1966)
  • CharkesN.D. et al.

    The pathologic basis of the strontium bone scan

    Journal of the American Medical Association

    (1968)
  • CharkesN.D. et al.

    Interpretation of the normal 99Tcm-polyphosphate rectilinear bone scan

    Radiology

    (1973)
  • CitrinD.L. et al.

    A comparison of phosphate bone scanning agents in normal subjects and patients with malignant disease

    British Journal of Radiology

    (1975)
  • CitrinD.L. et al.

    Dynamic studies with 99Tcm-H.E.D.P. in normal subjects and in patients with bone tumours

    Journal of Nuclear Medicine

    (1975)
  • CoxP.H.

    Abnormalities in skeletal uptake of 99Tcm-polyphosphate complexes in areas of bone associated with tissues which have been subjected to radiation therapy

    British Journal of Radiology

    (1974)
  • De NardoG.L.

    The 85Sr scintiscan in bone disease

    Annals of Internal Medicine

    (1966)
  • FrankelR.S. et al.

    ‘Normal’ bone radionuclide image with diffuse skeletal lymphoma. A case report

    Radiology

    (1974)
  • Cited by (0)

    *

    Based on a paper given to the Faculty of Radiologists, London, January 1975.

    View full text