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Dosimetry of yttrium-labelled radiopharmaceuticals for internal therapy: 86Y or 90Y imaging?

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Abstract

This paper reviews issues concerning 86Y positron emission tomography (PET), 90Y PET and 90Y bremsstrahlung imaging. Specific methods and corrections developed for quantitative imaging, for application in preclinical and clinical studies, and to assess 90Y dosimetry are discussed. The potential imaging capabilities with the radioisotopes 87Y and 88Y are also considered. Additional studies required to assess specific unaddressed issues are also identified.

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Authors and Affiliations

  1. Center of Nuclear Medicine, Université Catholique de Louvain, Av Hippocrate 10, 1200, Brussels, Belgium

    Stephan Walrand, Renaud Lhommel, Stanislas Pauwels & Francois Jamar

  2. Department of Physics, Royal Marsden NHS Foundation Trust, Sutton, Surrey, UK

    Glenn D. Flux

  3. Department of Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands

    Mark W. Konijnenberg, Roelf Valkema & Eric P. Krenning

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  1. Stephan Walrand
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  2. Glenn D. Flux
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Correspondence to Stephan Walrand.

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Walrand, S., Flux, G.D., Konijnenberg, M.W. et al. Dosimetry of yttrium-labelled radiopharmaceuticals for internal therapy: 86Y or 90Y imaging?. Eur J Nucl Med Mol Imaging 38 (Suppl 1), 57–68 (2011). https://doi.org/10.1007/s00259-011-1771-7

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