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Proposal for standardization of 123I-metaiodobenzylguanidine (MIBG) cardiac sympathetic imaging by the EANM Cardiovascular Committee and the European Council of Nuclear Cardiology

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An Erratum to this article was published on 17 November 2010

Abstract

This proposal for standardization of 123I-metaiodobenzylguanidine (iobenguane, MIBG) cardiac sympathetic imaging includes recommendations for patient information and preparation, radiopharmaceutical, injected activities and dosimetry, image acquisition, quality control, reconstruction methods, attenuation, scatter and collimator response compensation, data analysis and interpretation, reports, and image display. The recommendations are based on evidence coming from original or scientific studies whenever possible and as far as possible reflect the current state-of-the-art in cardiac MIBG imaging. The recommendations are designed to assist in the practice of performing, interpreting and reporting cardiac sympathetic imaging. The proposed standardization does not include clinical indications, benefits or drawbacks of cardiac sympathetic imaging, and does not address cost benefits or cost effectiveness; however, clinical settings of potential utility are mentioned. Standardization of MIBG cardiac sympathetic imaging should contribute to increasing its clinical applicability and integration into current nuclear cardiology practice.

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Authors and Affiliations

  1. Nuclear Medicine Department, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Sant Antoni M. Claret, 167, 08025, Barcelona, Spain

    Albert Flotats & Ignasi Carrió

  2. Nuclear Medicine Department, CHU Côte de Nacre, Caen, France

    Denis Agostini

  3. Nuclear Medicine Department, Bichat Hospital, Paris, France

    Dominique Le Guludec

  4. Cardiology Department, S. Maugeri Foundation, IRCCS, Scientific Institute of Veruno, Veruno, Italy

    Claudio Marcassa

  5. Nuclear Medicine Department, University Hospital Muenster, Münster, Germany

    Michael Schaffers

  6. Cardiology Department, Cardiology Centers of the Netherlands, Amsterdam, The Netherlands

    G. Aernout Somsen

  7. Nuclear Medicine Department, Gazi University, Ankara, Turkey

    Mustafa Unlu

  8. Nuclear Medicine Department, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

    Hein J. Verberne

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  1. Albert Flotats
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  2. Ignasi Carrió
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  3. Denis Agostini
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  9. Hein J. Verberne
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Correspondence to Albert Flotats.

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This proposal summarizes the views of the Cardiovascular Committee of the EANM and the European Council of Nuclear Cardiology, and reflects recommendations for which the EANM and the ESC cannot be held responsible. The recommendations should be taken in the context of good practice of nuclear medicine and do not substitute for national and international legal or regulatory provisions.

On behalf of the Cardiovascular Committee of the EANM and the European Council of Nuclear Cardiology.

An erratum to this article can be found at http://dx.doi.org/10.1007/s00259-010-1671-2

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Flotats, A., Carrió, I., Agostini, D. et al. Proposal for standardization of 123I-metaiodobenzylguanidine (MIBG) cardiac sympathetic imaging by the EANM Cardiovascular Committee and the European Council of Nuclear Cardiology. Eur J Nucl Med Mol Imaging 37, 1802–1812 (2010). https://doi.org/10.1007/s00259-010-1491-4

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