Abstract
Osteonecrosis may result from complications in a variety of pediatric diseases and, in the early stages of healing, may be characterized by inflammation and hyperemia. While traditionally assessed by bone scintigraphy, osteonecrosis may also present upon [F-18]2-fluoro-2-deoxyglucose PET/CT. Differentiation of osteonecrosis from metastatic lesions is important to ensure accurate disease staging and to avoid unnecessary imaging and biopsy. Osteonecrosis typically presents at the interface of weight-bearing joints after prolonged chemotherapy with corticosteroid administration, although prevalence is greater in adults than in children. We describe a case of unilateral osteonecrosis in the tibia of an adolescent lymphoma patient, which first presented on FDG-PET/CT imaging after 2 months of combination chemotherapy with corticosteroid administration. This report should aid in recognizing rapid-onset osteonecrosis with atypical sites of involvement in pediatric patients.
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Hong, T.S., Shammas, A., Navarro, O.M. et al. Osteonecrosis in an adolescent with non-Hodgkin lymphoma resembling a new metastatic lesion on 18F-FDG PET/CT. Pediatr Radiol 40 (Suppl 1), 27–29 (2010). https://doi.org/10.1007/s00247-010-1827-z
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DOI: https://doi.org/10.1007/s00247-010-1827-z