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Transplacental passage of non-ionic contrast agents resulting in fetal bowel opacification: a mimic of pneumoperitoneum in the newborn

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Abstract

Although animal studies suggest that non-ionic radiological contrast agents do not cross the placenta, case reports have documented transplacental passage of the non-ionic monomers iohexol and iopromide in humans. We report a case of presumed transplacental passage of the non-ionic monomer ioversol resulting in fetal bowel opacification and mimicking pneumoperitoneum.

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References

  1. ACR Committee on Drugs and Contrast Media (2004) Administration of contrast medium to pregnant or potentially pregnant patients. In: Manual on contrast media, version 5.0. American College of Radiology, pp 44–45

  2. Tauber U, Mutzel W, Schulze PE (1989) Whole body autoradiographic distribution studies on nonionic x-ray contrast agents in pregnant rats. Fortschr Geb Rontgenstrahlen Nuklearmed Erganzungsbd 128:215–219

    PubMed  CAS  Google Scholar 

  3. Bourrinet P, Dencausse A, Harvard P et al (1995) Transplacental passage and milk excretion of iobitridol. Invest Radiol 30:156–158

    Article  PubMed  CAS  Google Scholar 

  4. Moon AJ, Katzberg RW, Sherman MP (2000) Transplacental passage of iohexol. J Pediatr 136:548–549

    Article  PubMed  CAS  Google Scholar 

  5. Vanhaesebrouck P, Verstraete AG, De Praeter C et al (2005) Transplacental passage of a nonionic contrast agent. Eur J Pediatr 164:408–410

    Article  PubMed  Google Scholar 

  6. Dean PB (1977) Fetal uptake of an intravascular radiologic contrast medium. Rofo 127:267–270

    PubMed  CAS  Google Scholar 

  7. Kelleher J, Feczko PJ, Radkowski MA et al (1979) Neonatal intestinal opacification secondary to transplacental passage of urographic contrast medium. AJR 132:63–65

    PubMed  CAS  Google Scholar 

  8. Abitbol MM, Driscoll SG, Ober WB (1976) Placental lesions in experimental toxemia in the rabbit. J Obstet Gynecol 125:942–948

    CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Radiology, University of Miami Miller School of Medicine, Miami, FL, USA

    Brook J. Hill & George E. Abdenour Jr.

  2. Department of Clinical Radiology, Jackson Memorial Hospital, University of Miami Miller School of Medicine, 1611 NW 12th Ave., WW279, Miami, FL, 33136, USA

    Gaurav Saigal

  3. University of Miami Miller School of Medicine, Miami, FL, USA

    Sandip Patel

Authors
  1. Brook J. Hill
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  2. Gaurav Saigal
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  3. Sandip Patel
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  4. George E. Abdenour Jr.
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Corresponding author

Correspondence to Gaurav Saigal.

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Hill, B.J., Saigal, G., Patel, S. et al. Transplacental passage of non-ionic contrast agents resulting in fetal bowel opacification: a mimic of pneumoperitoneum in the newborn. Pediatr Radiol 37, 396–398 (2007). https://doi.org/10.1007/s00247-007-0422-4

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  • DOI: https://doi.org/10.1007/s00247-007-0422-4

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