TABLE 2

Effect of Drugs on Striatal 123I-Ioflupane Binding

Effect typeDrug
Possible increase in bindingOpioid: fentanyl
Eugeroic: modafinil
Antidepressants: bupropion, mazindol, radafaxine
Anticholinergic: benztropine
Anesthetics: isoflurane, ketamine, phencyclidine
Central nervous system stimulant: cocaine
Possible increase or decrease in bindingAdrenergic agonists: norepinephrine, phenylephrine
Amphetamines: d-amphetamine, methamphetamine, methylphenidate
Central nervous system stimulants: ephedrine, phentermine
No effectDopamine agonists
N-methyl-d-aspartate receptor blockers
Monoamine oxidase B inhibitors
Catechol-O-methyltransferase inhibitors
  • Adapted from Djang et al. (3).